Results 181 to 190 of about 124,281 (312)

Integrated transcriptomic analysis and experimental validation identify ACADL as a mitochondrial tumor suppressor via the FOXO3a/PUMA axis in lung adenocarcinoma. [PDF]

Eur J Med Res
Wang Y, Ding Y.
europepmc   +1 more source

Biocontrol for Shrimp Disease: Comprehensive Review and a Bacterial Disease Biocontrol Practice

Reviews in Aquaculture, Volume 18, Issue 3, June 2026.
ABSTRACT Biocontrol is a key strategy for disease control, as it is environmentally friendly and widely applicable. This review elaborates on biocontrol in aquaculture, particularly in shrimp culture. Biocontrol in shrimp culture mainly relies on four strategies: (i) direct kill pathogen by Bdellovibrio or bacteriophages; (ii) suppression of intestinal
Xinyi He, Jian He, Minghong Liu, Menghuang Xu, Jianjun Jiang, Minze Liao, Chengcheng Wu, Peiyun Han, Long Zhang, Shaoping Weng, Zhixun Guo, Jianguo He   +11 more
wiley   +1 more source

Digital Pathology-Based Comparison of PyRadiomics and HistomicsTK for Nuclei Classification in Melanoma Whole Slide Images. [PDF]

Int J Biomed Imaging
Finti A, Marinozzi F, Pasini G, Russo G, Stefano A, Bini F.   +5 more
europepmc   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, Volume 20, Issue 5, Page 1323-1346, May 2026.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Unraveling the miR-144-3p/PUMA pathway: a novel regulator of FDX1-mediated cuproptosis in colorectal cancer. [PDF]

Cell Oncol (Dordr)
Jia G, Li J, Jiang M, Liu N, Ding N, Jiang X, Zhang G, Tan X, Kang Y, Zhang L, Wang F, Zhang Y.   +11 more
europepmc   +1 more source

Does Your Classmatesʼ Early Childhood Education Experience Affect Your Non‐Cognitive/Socio‐Emotional Skills?

Asia &the Pacific Policy Studies, Volume 13, Issue 2, May 2026.
ABSTRACT We investigate whether having more classmates with ECE experience affects junior high school studentsʼ non‐cognitive/socio‐emotional skills. We draw on panel data from the China Education Panel Survey (CEPS) and leverage the exogenous variation in classroom ECE experience composition brought by the random assignment of students when they ...
Yuhe Guo, Chengfang Liu, Yalin Tang
wiley   +1 more source

Allosteric regulation of BH3-in-groove interactions by tail anchors of BCL-xL complexes limits BH3 mimetic antagonism. [PDF]

Nat Commun
Maillet L, Fétiveau A, Lalier L, Martin N, Barillé-Nion S, Guette C, Gautier F, Téletchéa S, Juin PP.   +8 more
europepmc   +1 more source

Fianlimab, a human lymphocyte activation gene‐3 monoclonal antibody, in combination with cemiplimab: Tumor‐specific expansion cohorts in advanced malignancies

Cancer, Volume 132, Issue 9, 1 May 2026.
Abstract Background The dose escalation phase of a first‐in‐human (FIH) study demonstrated acceptable safety and preliminary antitumor activity of fianlimab (anti‐lymphocyte activation gene‐3 [LAG‐3]) as monotherapy and in combination with cemiplimab (anti‐programmed cell death‐1 [PD‐1]). Here, the authors present safety and clinical activity data from
Tae Min Kim, Stephen K. Williamson, Kyriakos P. Papadopoulos, Omid Hamid, Grace K. Dy, Ray McDermott, Ariel Birnbaum, John M. Kaczmar, Nehal Lakhani, Danny Rischin, Debashis Sarker, Afshin Dowlati, Xin‐Hua Zhu, Jyoti Malhotra, Jean‐Francois Pouliot, Jayakumar Mani, Laura Brennan, Fang Fang, Shuquan Chen, Mark Salvati, Israel Lowy, Ahmed Khaled, Karl D. Lewis, Glenn Kroog, Matthew G. Fury, Byoung Chul Cho   +25 more
wiley   +1 more source

Trophic Duality: Taxonomic Segregation and Convergence in Prey Functional Traits Driving the Coexistence of Apex Predators. [PDF]

Biology (Basel)
Entringer H, Srbek-Araujo AC.
europepmc   +1 more source

Combined Inhibition of ATR and Ribonucleotide Reductase Induces Synergistic Antineoplastic Activity in Osteosarcoma Cells

Cancer Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background Osteosarcoma is the most common bone cancer in children and young adults. Its prognosis has not improved significantly since the introduction of the chemotherapy regimen established about 40 years ago, highlighting the need for new therapeutic strategies.
Natalie Aderhold, Lisa Immesberger, Sabine Becker, Till Milde, Bernd Gruhn, Jürgen Sonnemann   +5 more
wiley   +1 more source