Results 191 to 200 of about 124,281 (312)

Advancing Pharmacometrics in Africa: Insights and Perspectives From the 2025 Pharmacometrics Africa Conference

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 5, Page 1216-1222, May 2026.
Pharmacometrics (PMX) in Africa has transitioned from foundational capacity‐building to job creation, scientific leadership, regulatory influence, and health innovation. To accelerate this progress, the 2025 Pharmacometrics Africa Conference (PMXAC‐2025) convened key stakeholders to consolidate the continental PMX community, review progress in local ...
Babatunde Ayodeji Adeagbo   +12 more
wiley   +1 more source

Critical Discourse Analysis in Corporate Reports: Legitimation Strategies in the Context of Environmental Controversies

open access: yesCorporate Social Responsibility and Environmental Management, Volume 33, Issue 3, Page 3563-3581, May 2026.
ABSTRACT This study examines the use of environmental disclosure as a strategic tool to manage legitimacy crises in a mining company, adopting critical discourse analysis (CDA) as the main methodology. Focusing on a case of environmental disaster, this research reveals how corporate narratives can be manipulated to minimize responsibility and reinforce
Renata Luiza de Castilho Rossoni   +1 more
wiley   +1 more source

Testicular degeneration in a jaguarundi (Puma yagouaroundi): a histological and functional case study. [PDF]

open access: yesVet Res Commun
Pinzón-Osorio CA   +6 more
europepmc   +1 more source

Monkey Meltdowns: Do Tantrums Influence Maternal Investment in Bearded Capuchin Monkeys?

open access: yesDevelopmental Psychobiology, Volume 68, Issue 3, May 2026.
ABSTRACT Tantrums are widely discussed in human development literature and are typically defined as displays of frustration or anger. In behavioral ecology, they are hypothesized to function as a strategy for securing greater maternal investment. Infant primates often exhibit tantrums when their attempts to obtain maternal care are rejected.
Mábia B. Cera   +5 more
wiley   +1 more source

NDRG2 upregulation induces astrocytic apoptosis via AKT inhibition and FoxO3a-Puma activation in depression. [PDF]

open access: yesCommun Biol
Wang Z   +14 more
europepmc   +1 more source

Deciphering Bax Dynamics: Regulation, Retrotranslocation, and Mitochondrial Interplay in the Commitment to Apoptosis: A Narrative Review

open access: yesHealth Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background The apoptotic pathway mediated by mitochondria depends on the activation of pro‐apoptotic Bcl‐2 proteins Bax and Bak. When they permeabilize the outer mitochondrial membrane (OMM), mitochondrial dysfunction occurs, leading to caspase activation.
Mehrin Haque Tanisha   +4 more
wiley   +1 more source

From Platelet Toxicity to Precision Targeting: Evolving Strategies to Overcome Thrombocytopenia in BCL‐2/BCL‐XL Inhibition

open access: yesHealth Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background Simultaneous blockade of the anti‐apoptotic proteins BCL‐2 and BCL‐XL has been shown to be efficacious in preclinical and clinical trials for tumors that are co‐dependent on their survival pathways, although clinical development has been limited owing to dose‐limiting thrombocytopenia associated with BCL‐XL inhibition.
Md Mohiuddin
wiley   +1 more source

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