Results 191 to 200 of about 124,281 (312)
Pharmacometrics (PMX) in Africa has transitioned from foundational capacity‐building to job creation, scientific leadership, regulatory influence, and health innovation. To accelerate this progress, the 2025 Pharmacometrics Africa Conference (PMXAC‐2025) convened key stakeholders to consolidate the continental PMX community, review progress in local ...
Babatunde Ayodeji Adeagbo +12 more
wiley +1 more source
Meningeal lymphatic vessel dysfunction exacerbates brain injury in CVST mice via endoplasmic reticulum and oxidative stress pathways. [PDF]
Ying J +7 more
europepmc +1 more source
ABSTRACT This study examines the use of environmental disclosure as a strategic tool to manage legitimacy crises in a mining company, adopting critical discourse analysis (CDA) as the main methodology. Focusing on a case of environmental disaster, this research reveals how corporate narratives can be manipulated to minimize responsibility and reinforce
Renata Luiza de Castilho Rossoni +1 more
wiley +1 more source
Testicular degeneration in a jaguarundi (Puma yagouaroundi): a histological and functional case study. [PDF]
Pinzón-Osorio CA +6 more
europepmc +1 more source
Monkey Meltdowns: Do Tantrums Influence Maternal Investment in Bearded Capuchin Monkeys?
ABSTRACT Tantrums are widely discussed in human development literature and are typically defined as displays of frustration or anger. In behavioral ecology, they are hypothesized to function as a strategy for securing greater maternal investment. Infant primates often exhibit tantrums when their attempts to obtain maternal care are rejected.
Mábia B. Cera +5 more
wiley +1 more source
Break it to make it: Rewiring bacterial metabolism for the growth-coupled biosynthesis of xanthommatin animal pigments. [PDF]
Calhoun JT, McKinnie SMK.
europepmc +1 more source
NDRG2 upregulation induces astrocytic apoptosis via AKT inhibition and FoxO3a-Puma activation in depression. [PDF]
Wang Z +14 more
europepmc +1 more source
ABSTRACT Background The apoptotic pathway mediated by mitochondria depends on the activation of pro‐apoptotic Bcl‐2 proteins Bax and Bak. When they permeabilize the outer mitochondrial membrane (OMM), mitochondrial dysfunction occurs, leading to caspase activation.
Mehrin Haque Tanisha +4 more
wiley +1 more source
ABSTRACT Background Simultaneous blockade of the anti‐apoptotic proteins BCL‐2 and BCL‐XL has been shown to be efficacious in preclinical and clinical trials for tumors that are co‐dependent on their survival pathways, although clinical development has been limited owing to dose‐limiting thrombocytopenia associated with BCL‐XL inhibition.
Md Mohiuddin
wiley +1 more source

