Results 191 to 200 of about 28,540 (263)

Goniothalamin as a Styryl‐Lactone Toxicophore in Cancer Models: Electrophile‐Driven DNA Damage, Reactive Oxygen Species–Endoplasmic Reticulum Stress Signaling and Detoxification‐Relevant Safety Considerations

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Goniothalamin (GTN) exerts anticancer effects by promoting reactive oxygen species (ROS) generation, glutathione (GSH) depletion, DNA damage, endoplasmic reticulum (ER) stress, and mitochondrial dysfunction. These interconnected events trigger apoptosis, necroptosis, anoikis, and autophagy, while modulating mitogen‐activated protein kinase (MAPK ...
Nataša Joković   +6 more
wiley   +1 more source

Fire‐induced shifts in activity patterns of predators and prey in the Brazilian Pantanal

open access: yesThe Journal of Wildlife Management, Volume 90, Issue 6, August 2026.
Using camera trap data, we observed that 5 of 6 prey species showed statistically significant changes in temporal activity patterns, while jaguars were the only predator species to adjust activity when comparing pre‐fire and post‐fire periods in an isolated rocky formation in the Pantanal region.
Sergio Eduardo Barreto de Aguiar   +12 more
wiley   +1 more source

Behavioral responses of black bears to human presence and infrastructure in Yosemite National Park

open access: yesThe Journal of Wildlife Management, Volume 90, Issue 6, August 2026.
Using GPS collar data from black bears in Yosemite National Park, we examined how bear spatiotemporal activity in relation to human development shifted during the COVID‐19 park closure in 2020. In the absence of visitors, bears maintained consistent landscape‐scale space use but altered fine‐scale spatial and temporal behaviors.
Jennifer R. Green   +9 more
wiley   +1 more source

NEK1 Promotes Ovarian Cancer Progression via p53 Suppression While Enhancing Sensitivity to Genotoxic Therapy. [PDF]

open access: yesCurr Issues Mol Biol
Song H   +9 more
europepmc   +1 more source

This is fine: Mule deer and elk do not substantially change their behavior in response to active wildfires

open access: yesThe Journal of Wildlife Management, Volume 90, Issue 6, August 2026.
During an outbreak of 7 wildfires in eastern Oregon, USA, we analyzed the home range and movement patterns of mule deer and elk before, during, and immediately after wildfires. Mule deer maintained high site fidelity during the wildfire but used their home range more uniformly and had higher daily displacement than deer unaffected by wildfire.
Jacob W. Dittel, Darren A. Clark
wiley   +1 more source

Cougar density on the Oregon Coast: Using dead recovery modeling in an open population

open access: yesThe Journal of Wildlife Management, Volume 90, Issue 6, August 2026.
The primary objective of this study was to determine cougar density in western Oregon. Our results demonstrate that integrating DNA collected via bio‐darting, mandatory hunter‐harvest check‐ins, and GPS collar data into the OPCR2 is a reliable method for estimating cougar densities in densely forested coastal systems.
Jason A. Kirchner   +4 more
wiley   +1 more source

NDRG2 upregulation induces astrocytic apoptosis via AKT inhibition and FoxO3a-Puma activation in depression. [PDF]

open access: yesCommun Biol
Wang Z   +14 more
europepmc   +1 more source

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