Goniothalamin (GTN) exerts anticancer effects by promoting reactive oxygen species (ROS) generation, glutathione (GSH) depletion, DNA damage, endoplasmic reticulum (ER) stress, and mitochondrial dysfunction. These interconnected events trigger apoptosis, necroptosis, anoikis, and autophagy, while modulating mitogen‐activated protein kinase (MAPK ...
Nataša Joković +6 more
wiley +1 more source
Trophic Duality: Taxonomic Segregation and Convergence in Prey Functional Traits Driving the Coexistence of Apex Predators. [PDF]
Entringer H, Srbek-Araujo AC.
europepmc +1 more source
Fire‐induced shifts in activity patterns of predators and prey in the Brazilian Pantanal
Using camera trap data, we observed that 5 of 6 prey species showed statistically significant changes in temporal activity patterns, while jaguars were the only predator species to adjust activity when comparing pre‐fire and post‐fire periods in an isolated rocky formation in the Pantanal region.
Sergio Eduardo Barreto de Aguiar +12 more
wiley +1 more source
Behavioral responses of black bears to human presence and infrastructure in Yosemite National Park
Using GPS collar data from black bears in Yosemite National Park, we examined how bear spatiotemporal activity in relation to human development shifted during the COVID‐19 park closure in 2020. In the absence of visitors, bears maintained consistent landscape‐scale space use but altered fine‐scale spatial and temporal behaviors.
Jennifer R. Green +9 more
wiley +1 more source
NEK1 Promotes Ovarian Cancer Progression via p53 Suppression While Enhancing Sensitivity to Genotoxic Therapy. [PDF]
Song H +9 more
europepmc +1 more source
During an outbreak of 7 wildfires in eastern Oregon, USA, we analyzed the home range and movement patterns of mule deer and elk before, during, and immediately after wildfires. Mule deer maintained high site fidelity during the wildfire but used their home range more uniformly and had higher daily displacement than deer unaffected by wildfire.
Jacob W. Dittel, Darren A. Clark
wiley +1 more source
Meningeal lymphatic vessel dysfunction exacerbates brain injury in CVST mice via endoplasmic reticulum and oxidative stress pathways. [PDF]
Ying J +7 more
europepmc +1 more source
Cougar density on the Oregon Coast: Using dead recovery modeling in an open population
The primary objective of this study was to determine cougar density in western Oregon. Our results demonstrate that integrating DNA collected via bio‐darting, mandatory hunter‐harvest check‐ins, and GPS collar data into the OPCR2 is a reliable method for estimating cougar densities in densely forested coastal systems.
Jason A. Kirchner +4 more
wiley +1 more source
NDRG2 upregulation induces astrocytic apoptosis via AKT inhibition and FoxO3a-Puma activation in depression. [PDF]
Wang Z +14 more
europepmc +1 more source

