Results 211 to 220 of about 43,136 (308)

Astrocytic mGluR5 Regulation of Synaptic Transmission is Activity‐Dependent in Adult Rats

open access: yesGlia, Volume 74, Issue 8, August 2026.
In adulthood, astrocytic mGluR5 increases synaptic efficacy through presynaptic A2ARs. This occurs when a small number of synapses are activated simultaneously. This pathway is abolished when numerous synapses are recruited. ABSTRACT Data accumulated over the last two decades have demonstrated that astrocytes play key roles in the regulation of ...
Sarah Mountadem   +18 more
wiley   +1 more source

Ecology of reintroduced Rocky Mountain bighorn sheep in Dinosaur National Monument La Ecología de Borrego Cimarron de las Montañas Rocosas Reintroducido en el Monumento Nacional de Dinosaurio

open access: yesWildlife Monographs, Volume 223, Issue 1, August 2026.
We synthesized GPS telemetry, genetic, and pathogen data to evaluate metapopulation processes in a reintroduced Rocky Mountain bighorn sheep (Ovis canadensis canadensis) population in Dinosaur National Monument. We estimated subpopulation‐specific abundances and found 4 small subpopulations with high genetic diversity, partial connectivity, and ...
Sarah L. Carroll   +8 more
wiley   +1 more source

Systematic review and scoring‐based selection of pharmacokinetic models for precision dosing of vancomycin in neonates and children

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 7, Page 2028-2048, July 2026.
This systematic review identified 112 population pharmacokinetic models of vancomycin in neonates and children. To support rational model selection for model‐informed precision, we developed and applied expert‐driven, transparent criteria that integrate both methodological rigour and clinical relevance.
Zoë Vander Elst   +8 more
wiley   +1 more source

Predicted genetic consequences of alternative population control strategies for North American plains bison in Yellowstone National Park

open access: yesThe Journal of Wildlife Management, Volume 90, Issue 5, July 2026.
Management of bison in Yellowstone National Park under the available strategies that maintained ≥3,500 individuals (1:1 sex ratio), removed <40% of the population at a time and prioritized relatives for removal were predicted to maintain genetic variation at levels consistent with long‐term conservation (>95% of existing variation).
Shawna J. Zimmerman   +2 more
wiley   +1 more source

Rates and controls of methane emission from four Pacific northwest reservoirs with contrasting management regimes

open access: yesLimnology and Oceanography Letters, Volume 11, Issue 4, July 2026.
Abstract Although collectively reservoirs constitute a globally significant source of anthropogenic methane (CH4), there are still few investigations of reservoir CH4 fluxes and their controls that span multiple seasons, years, and reservoir types. Here we present results from a 2‐yr study of diffusive and ebullitive CH4 fluxes in four contrasting ...
David E. Ballenger, John A. Harrison
wiley   +1 more source

Urologic Bacteriome: The Hero or the Villain in Prostate Cancer Onset, Progression, and Treatment?

open access: yesMedicinal Research Reviews, Volume 46, Issue 4, Page 1111-1151, July 2026.
ABSTRACT Prostate cancer (PCa) is the second most frequently diagnosed cancer in men worldwide and the fifth leading cause of cancer‐related mortality, presenting urgent unmet clinical needs in diagnosis and treatment. The recognition of the microbiome as a key factor in human health has prompted numerous studies, revealing an exciting new approach to ...
Lara R. S. Fonseca   +6 more
wiley   +1 more source

Individual Identification of Prey in Carnivore Scats

open access: yesMolecular Ecology Resources, Volume 26, Issue 5, July 2026.
ABSTRACT Noninvasive genetic sampling is widely used in ecology and conservation to identify predators and their diets but recovering individual‐level information from consumed prey remains largely unexplored. We evaluated whether individual prey can be reliably genotyped from carnivore scats and assessed limitations associated with degraded and mixed ...
Charlotte E. Eriksson   +4 more
wiley   +1 more source

Whole Blood Transcriptomic Response to Perioperative Dexamethasone in Total Knee Arthroplasty: A Targeted Panel Analysis

open access: yesActa Anaesthesiologica Scandinavica, Volume 70, Issue 6, July 2026.
ABSTRACT Background Changes in the transcriptome of immune cells are predictive of clinical outcomes. These effects may be surgery‐specific and possibly modulated by glucocorticoids. We investigated the immune response and the impact of dexamethasone on the response in patients undergoing total knee arthroplasty (TKA). Methods The transcript levels (n =
Asger Krog Mølgaard   +9 more
wiley   +1 more source

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