Results 221 to 230 of about 124,281 (312)

Mitochondrial Homeostasis in Pancreatic β Cell Function: Mechanisms and Therapeutic Targets for Diabetes

Journal of Diabetes, Volume 18, Issue 5, May 2026.
This review highlights mitochondrial dysfunction as a central driver of pancreatic β cell failure in diabetes, caused by disrupted mitochondrial quality control (MQC), oxidative stress, and impaired organelle communication. Emerging therapies, such as DRAK2 inhibitors and metabolic reprogramming agents, show promise in restoring β cell function by ...
Ruihan Li, Bingqian Zhang, Yuxin Zhang, Yang Yang, Yuting Lu, Jingya Li   +5 more
wiley   +1 more source

Correction for Hao et al., Synthetical lethality of Werner helicase and mismatch repair deficiency is mediated by p53 and PUMA in colon cancer. [PDF]

Proc Natl Acad Sci U S A
europepmc   +1 more source

State and disturbance estimation with supertwisting sliding mode control for frequency regulation in hydrogen based microgrids. [PDF]

Sci Rep
Taher AM, Hasanien HM, Al-Gahtani SF, Ali ZM, Zobaa AF, Aleem SHEA.   +5 more
europepmc   +1 more source

State‐and‐transition simulation models: How can we use them to assess ecosystem condition and support nature markets

Methods in Ecology and Evolution, Volume 17, Issue 5, Page 1359-1375, May 2026.
Abstract The world is experiencing a biodiversity crisis. Steep declines in habitat quality and ecosystem services have resulted in interest in markets to help fund ecological restoration. One way that ecological restoration is assessed is through indicators of ecosystem condition, namely, a measurement of how different a landscape is from its ...
James M. Furlaud, Katrina Szetey, Kristen J. Williams, Louis Provencher, Suzanne M. Prober, Anna E. Richards   +5 more
wiley   +1 more source

Utilization of Child-Appropriate Medicines: Use of Pediatric Use Marketing Authorisation (PUMA) Products in Croatia. [PDF]

J Clin Med
Belančić A, Kučan Štiglić M, Rešić A, Fajkić A, Vitezić D.   +4 more
europepmc   +1 more source

Perp Deficiency Induces Defective Negative Selection and Autoimmune Arthritis in Aged Mice

Aging Cell, Volume 25, Issue 5, May 2026.
Perp deficiency promotes age‐related autoimmunity. ABSTRACT Thymic negative selection is characterized by the apoptosis of autoreactive thymocytes and plays a critical role in maintaining self‐tolerance. Numerous apoptosis‐related genes influence cell fate during T‐cell development.
Yan Zhou, Junrong Li, Xiao Leng, Jiao Shi, Gan Zhang, Shan Chen, Dong Liu, Qian Deng, Yan He, Guixiu Shi, Ying Xu, Yuan Liu, Yantang Wang   +12 more
wiley   +1 more source

Postmortem Abdominal Ultrasound in Healthy Wild Mammals for Application in Forensic Veterinary Medicine. [PDF]

Vet Med Int
Ferrari M, Reis STJ, Borges NC, Ribas LM, de Sant'Ana FJF.   +4 more
europepmc   +1 more source

Agrarian counterpoint

American Ethnologist, Volume 53, Issue 2, Page 171-182, May 2026.
Abstract In Colombia's northeastern borderlands, agrarian economies shape how disease risk and stigma are understood and managed. As shown in ethnographic fieldwork in and around the Catatumbo region, cutaneous leishmaniasis—a sandfly‐transmitted disease that produces chronic skin lesions—appears in two radically different guises across adjacent ...
Javier Lezaun, Lina Pinto‐García
wiley   +1 more source

DNA damage response signaling in oocytes from an oncofertility perspective†. [PDF]

Biol Reprod
Song YS, Zhang J, Bo Y, Zhang Q, Kim SY, Xiao S.   +5 more
europepmc   +1 more source

Neighbors to nature: A case study of recreation‐wildlife co‐existence in the Greater Yellowstone Ecosystem

Conservation Science and Practice, Volume 8, Issue 5, May 2026.
We monitored medium to large mammal and human activity to assess impacts of recreation and inform management, deploying 27 trail cameras along multi‐use non‐motorized recreational trails for 2.5 years in a heavily used area within the Greater Yellowstone Ecosystem, USA.
Courtney L. Larson, Trevor D. S. Bloom, Ashley Egan, Tim Farris, Kate Gersh, Linda Merigliano, Chris Owen, Renee Seidler, Hilary Turner   +8 more
wiley   +1 more source