Results 231 to 240 of about 43,136 (308)

Allosteric regulation of BH3-in-groove interactions by tail anchors of BCL-xL complexes limits BH3 mimetic antagonism. [PDF]

Nat Commun
Maillet L, Fétiveau A, Lalier L, Martin N, Barillé-Nion S, Guette C, Gautier F, Téletchéa S, Juin PP.   +8 more
europepmc   +1 more source

Vitamin D receptor signaling in inflammatory senescence–associated skin aging: Mechanisms and therapeutic potentials

Journal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
Vitamin D receptor (VDR) signaling is implicated in inflammatory senescence‐associated skin aging, a growing health concern in aging populations where cellular senescence and chronic inflammation converge to create complex pathophysiological conditions.
Liancheng Guan, Fan Yang, Meijuan Li, Yujia Chen, Zexin Zhao, Hongxia Li, Deping Luo, Qian Li, Yunzhi Chen   +8 more
wiley   +1 more source

NEK1 Promotes Ovarian Cancer Progression via p53 Suppression While Enhancing Sensitivity to Genotoxic Therapy. [PDF]

Curr Issues Mol Biol
Song H, Wang X, Yang A, Ren X, Zhou X, Qiu Y, Cai Y, Gao C, Zhou G, Cao P.   +9 more
europepmc   +1 more source

Lysine lactylation‐mediated post‐translational modification: Molecular mechanisms and therapeutic target exploration in tumour drug resistance

Clinical and Translational Medicine, Volume 16, Issue 6, June 2026.
Lysine lactylation (Kla) serves as a metabolic–epigenetic switch governed by writer–eraser–reader regulatory systems, directly connecting the Warburg effect to diverse forms of tumour drug resistance. Intratumoural lactylation critically contributes to treatment failure in chemotherapy, targeted therapy and immunotherapy.
Juan Li, Yan Shang, Haojie Wu, Shenglong Yang, Maiqun Zuo, Hailong Zhao   +5 more
wiley   +1 more source

Integrating Niche Dimensions to Advance the Ecological Study of the Americas' Smallest Cat: The Guigna in Argentine Patagonia

Ecology and Evolution, Volume 16, Issue 6, June 2026.
We present our findings from the first multi‐annual survey of guigna in Argentine Patagonia. We found that habitat use for guignas was negatively affected by the presence of co‐predators and open vegetation; conversely, it was positively affected by the occurrence of thick forests and the presence of potential prey.
M. M. Guerisoli, G. Bauer, S. Sarra Pistone, E. Buffa, C. Bonaglia, A. J. Giordano, M. I. Schiaffini   +6 more
wiley   +1 more source

Trophic Duality: Taxonomic Segregation and Convergence in Prey Functional Traits Driving the Coexistence of Apex Predators. [PDF]

Biology (Basel)
Entringer H, Srbek-Araujo AC.
europepmc   +1 more source

Natives Against Invaders: Shared Use of Space and Temporal Segregation of Clouded Tiger‐Cats (Leopardus pardinoides) and Domestic Dogs (Canis familiaris) in an Isolated Protected Area

Ecology and Evolution, Volume 16, Issue 6, June 2026.
We studied the spatial and temporal relationships between clouded tiger‐cats and dogs in an isolated protected area of Colombia. Dogs influenced the activity patterns of clouded tiger‐cats but not their habitat use. Conservation actions should be directed to mitigate potential contact between both species.
J. C. Cepeda‐Duque, A. M. López‐Barrera, E. Arango‐Correa, J. F. Hernández‐Fitzgerald, V. López‐Velasco, L. A. Fox‐Rosales, T. G. de Oliveira   +6 more
wiley   +1 more source

Meningeal lymphatic vessel dysfunction exacerbates brain injury in CVST mice via endoplasmic reticulum and oxidative stress pathways. [PDF]

Front Immunol
Ying J, Li J, Wu X, Chen X, Zhang H, Wei L, Jing J, Wang S.   +7 more
europepmc   +1 more source

Testicular degeneration in a jaguarundi (Puma yagouaroundi): a histological and functional case study. [PDF]

Vet Res Commun
Pinzón-Osorio CA, Cortes-Beltran D, Bellido-Quispe DK, Mondadori RG, Lozano-Márquez H, Zambrano-Varón J, Jiménez-Escobar C.   +6 more
europepmc   +1 more source