Results 241 to 250 of about 43,136 (308)
NDRG2 upregulation induces astrocytic apoptosis via AKT inhibition and FoxO3a-Puma activation in depression. [PDF]
Wang Z +14 more
europepmc +1 more source
The aim of this review is to critically evaluate the therapeutic potential of Ficus benghalensis L. by integrating ethnomedicinal knowledge with contemporary scientific evidence. The objectives are to summarize its phytochemical profile, analyze antioxidant, antimicrobial, antidiabetic, anti‐inflammatory, and anticancer activities, elucidate underlying
Zainab Ali +9 more
wiley +1 more source
Break it to make it: Rewiring bacterial metabolism for the growth-coupled biosynthesis of xanthommatin animal pigments. [PDF]
Calhoun JT, McKinnie SMK.
europepmc +1 more source
This article reviews the pivotal role of post‐translational modifications of proteins in the development and progression of hematologic malignancies, and explores their clinical translation potential as novel biomarkers and therapeutic targets. ABSTRACT Post‐translational modifications (PTMs) of proteins have emerged as critical regulators in the ...
Yuxuan Han +6 more
wiley +1 more source
Oxidative Stress in the Tumor Immune Microenvironment: Mechanisms and Therapeutic Perspectives
Oxidative stress is involved in several key processes in cancer, including redox regulation, DNA damage, post‐translational modifications, transcriptional regulation, epigenetic modifications, metabolic reprogramming, cell death, and immune modulation. These mechanisms collectively influence tumor progression, immune evasion, and therapeutic responses,
Zhen Wang +14 more
wiley +1 more source
Heart disease diagnosis and categorization from ECG signals using hybrid Fuzzy-CNN machine optimized by meta-heuristic algorithms. [PDF]
Davani M +3 more
europepmc +1 more source
Ribosomal Proteins in Cell Biology and Cancer
The functions of ribosomal proteins (RPs) extend beyond the conventional translation process, as they also regulate gene expression, stress responses, and disease progression. Dysregulation of RPs contributes to the onset and progression of various diseases, including cancer and ribosomopathies, underscoring their dual role as critical disease ...
Ao Zhang +4 more
wiley +1 more source
Neuroprotection of IGF-1 in neonatal hypoxic-ischemic brain injury through downregulation of FoXO3a-PUMA pathway. [PDF]
Tang Y +8 more
europepmc +1 more source
Evaluating commonly used tools to quantify human activity for protected area management
Abstract Recreation in protected areas (PAs) is growing worldwide, potentially conflicting with wildlife and ecosystem protection. Efficiently estimating human activity in PAs is crucial for balancing a dual mandate of supporting visitor access and biodiversity, but managers lack clear recommendations about the conditions under which specific tools are
Alys Granados +17 more
wiley +1 more source

