Results 251 to 260 of about 43,136 (308)

Exploring the impact of hAMSCs secretome on Panc1 cells via TNF-α/NF-κB (p50/p65)/Caspase 3 signaling pathways: An <i>in vitro</i> study. [PDF]

Biochem Biophys Rep
Khalafi A, Safari F.
europepmc   +1 more source

Covalent drug rescue of multiple p53 mutants by stabilizing vinyl sulfone fragments hints to a specific refolding mechanism for R282W

Protein Science, Volume 35, Issue 6, June 2026.
Abstract The tumor suppressor protein p53 plays a crucial role in cell cycle regulation. In approximately 50% of all tumors, mutations in p53 are observed. Although the top hot spot mutations impair DNA binding, other mutations affect the thermal stability of the protein, leading to its rapid denaturation in physiological conditions.
Jason Stahlecker, Theresa Klett, Robert Spiegel, Martin Schwer, Finn Mier, Sven Aldea, Benedikt Masberg, Michael Lämmerhofer, Thilo Stehle, Frank M. Böckler   +9 more
wiley   +1 more source

Book Review: The Cougar Conundrum: Sharing the World with a Successful Predator

California Fish and Wildlife Journal, 2020
Vernon C. Bleich
doaj  

Novel antagonist APG-115 targets MDM2-p53 to induce p53-mediated apoptosis and radiosensitization in colorectal cancer. [PDF]

Clin Exp Med
Yi H, Han Y, Wang X, Li Q, Xiong L, Li S.   +5 more
europepmc   +1 more source

ATGL sensitizes hepatocellular carcinoma cells to genotoxic drugs by modulating p53 acetylation/phosphorylation status. [PDF]

Cell Death Discov
Castelli S, De Cristofaro A, Desideri E, Salvi E, Ciccarone F, Ciriolo MR.   +5 more
europepmc   +1 more source

Wildlife Diseases: Pathology and Diagnostic Investigation. [PDF]

Animals (Basel)
Domenis L, Robetto S.
europepmc   +1 more source

A 2100‐km jaguar journey redefines mobility and large‐scale conservation priorities during large carnivore dispersal

Ecology, Volume 107, Issue 6, June 2026.
Jon Morant, Esther Sebastián‐González, Leandro Reverberi Tambosi, Alan Eduardo de Barros, Renato A. Moreira, Francesca Belem Lopes Palmeira, Douglas dos Santos Silva, Tiago J. Silveira, Anah T. A. Jácomo, Leandro Silveira   +9 more
wiley   +1 more source

CAPTURE and PUMA as Case-Finding Tools in Patients at Risk of COPD-A Multicenter Mexican Experience. [PDF]

J Clin Med
Cortes-Telles A, Juarez-de-Dios I, Figueroa-Hurtado E, Ortiz-Farias DL, Alvarez-Pinto J, Olaya-López E.   +5 more
europepmc   +1 more source

Correction for Hao et al., Synthetical lethality of Werner helicase and mismatch repair deficiency is mediated by p53 and PUMA in colon cancer. [PDF]

Proc Natl Acad Sci U S A
europepmc   +1 more source

Targeting CHD1L suppresses prostate cancer progression via the FOXO3-PUMA axis. [PDF]

J Transl Med
Hui P, Lai Y, Fan H, Yan Q, Yang Y, Chen Z, Hou Y, Kuang Y.   +7 more
europepmc   +1 more source