Results 61 to 70 of about 1,833 (248)

An Accessible Microfluidic Platform for the Generation of Polarized Brain Organoids

open access: yesAdvanced Materials Technologies, EarlyView.
This study presents an accessible double‐gradient microfluidic device that enables controlled morphogen delivery and spatially polarized differentiation in brain organoids. By integrating a pump‐free design and stable fabrication method, the platform generates dorsal–ventral neuronal asymmetry, offering a reproducible and versatile approach to model ...
Daniel Pérez‐Calixto   +6 more
wiley   +1 more source

Slab thickness-shear reinforcement interaction on shear strength of interior slab-column connections

open access: yesJournal of Engineering and Applied Science
The effects of slab thickness and punching shear reinforcement ratio on the individual contributions of concrete and reinforcement on punching shear strength of interior slab-column connections are theoretically investigated.
Osman M. Ramadan   +2 more
doaj   +1 more source

Additive Manufacturing of Patient‐Specific Intracranial Aneurysm Cell Culture Models

open access: yesAdvanced Materials Technologies, EarlyView.
Patient‐specific intracranial aneurysm models were fabricated using chocolate moulding, 3D printed water‐soluble cores, and direct resin 3D printing. Moulding PDMS around sacrificial cores made of chocolate or 3D printed water‐soluble resin yielded accurate, expandable, and endothelializable models that outperformed resin‐based approaches.
Chloe M. de Nys   +6 more
wiley   +1 more source

Post-Punching Mechanisms of Slab-Column Joints Under Upward and Downward Punching Actions

open access: yes, 2021
Progressive collapse of reinforced concrete flat plate systems can be significantly influenced by the post-punching performance of their slab–column joints under large deformations.
Guan, Hong   +5 more
core   +1 more source

Lymphoid‐Tissue‐on‐Chip Recapitulates Human Antibody Responses In Vitro

open access: yesAdvanced Science, EarlyView.
The presented lymphoid‐tissue‐on‐chip system allows culture of primary human tonsil cells at organotypic high density under perfusion for up to 4 weeks, emulates immune response to soluble vaccines and vaccination via peripheral antigen‐presenting cells and represents a useful tool to assess cellular interactions during homeostasis, immune responses ...
Claudia Teufel   +15 more
wiley   +1 more source

A Bioinspired Three‐Dimensional High‐Curvature Nano‐Interface Integrated Microfluidic Chip for Small Extracellular Vesicles Enrichment and Machine Learning‐Assisted Prostate Cancer Precision Diagnosis

open access: yesAdvanced Science, EarlyView.
A biotin‐modified artificial insertion peptide functionalized three‐dimensional high‐curvature‐TiO2 nano‐interface was engineered in a microfluidic chip to improve the isolation efficiency of small extracellular vesicles (sEVs). This chip balanced affinity, releasability, and extendibility, enabling high‐throughput recovery of sEVs for downstream ...
Le Wang   +7 more
wiley   +1 more source

Punching shear capacity of expanded polystyrene (EPS) lightweight concrete flat slabs without shear reinforcement

open access: yesAdvances in Mechanical Engineering, 2023
This work presents an experimental and theoretical study on the punching shear behavior of Lightweight Concrete Slabs. Lightweight obtained using Expanded polystyrene (EPS) beads as partial coarse aggregate’s replacement, without adding supplementary ...
Faris Rashied Ahmed
doaj   +1 more source

Dynamic Self‐Clickable Decellularized Matrix Hydrogels for Regulating Vascularity and Enhancing Muscle Regeneration

open access: yesAdvanced Science, EarlyView.
Dynamic decellularized hydrogels are prepared using bovine decellularized small intestine submucosa (SIS) norbornene (dSIS‐NB). Bovine dSIS contained significant amounts of disulfide‐rich fibrillin‐I, enabling ‘self‐clickable’ thiol‐norbornene gelation and spatiotemporal tuning of hydrogel physicochemical properties.
Van Thuy Duong   +4 more
wiley   +1 more source

Punching shear resistance of reinforced concrete footings: evaluation of design codes

open access: yesRevista IBRACON de Estruturas e Materiais, 2018
Punching is a possible failure mode for slender footings and it may lead a structure to ruin through progressive collapse. Although footing present different geometric characteristics, their punching shear design is based on the empirical methods used ...
D. F. A. SANTOS   +2 more
doaj   +2 more sources

A Soft Mechanoluminescent Skin for High‐Resolution Optical Tactile Sensing in Human–Machine Interaction

open access: yesAdvanced Science, EarlyView.
A soft mechanoluminescent tactile sensor that converts force directly into light is presented, enabling imaging‐based, wiring‐free touch sensing. By integrating a flexible ML‐skin with CMOS readout, the system achieves high sensitivity, fast response, and high spatial resolution, while maintaining structural simplicity and energy efficiency, offering a
Yu Feng   +11 more
wiley   +1 more source

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