Results 71 to 80 of about 9,167 (257)

Advanced 3D Platforms for Modeling CNS Neuroinflammation: Cell Integration, Techniques, and Challenges

Advanced Healthcare Materials, EarlyView.
This review summarizes the roles of key central nervous system cell types, the extracellular matrix, and the blood‐brain barrier in neuroinflammation, and their integration into diverse 3D culture systems. It examines major incorporation strategies, including direct co‐culture, hydrogel encapsulation, transwell migration assays, and bioprinting ...
Emmanuelle D. Aiyegbusi, Julia Di Stefano, Dearbhaile Dooley   +2 more
wiley   +1 more source

Slab thickness-shear reinforcement interaction on shear strength of interior slab-column connections

Journal of Engineering and Applied Science
The effects of slab thickness and punching shear reinforcement ratio on the individual contributions of concrete and reinforcement on punching shear strength of interior slab-column connections are theoretically investigated.
Osman M. Ramadan, Rasha T. S. Mabrouk, Gehad S. Younis   +2 more
doaj   +1 more source

A Long‐Lived Human Neurovascular PENTA Culture Model Captures Incomplete Vascular Repair and Glia‐Associated Signaling After Traumatic Brain Injury

Advanced Healthcare Materials, EarlyView.
A long‐lived, five‐cell‐type human neurovascular (PENTA) model recreates vascular disorganization and incomplete repair after traumatic brain injury (TBI). By integrating endothelial, glial, neuronal, and immune components within a 3D scaffold, the platform enables time‐resolved analysis of neurovascular remodeling and provides a human‐relevant system ...
Daniel S. Hinrichsen, Sunghyun Jun, Colleen M. Arrasmith, Charitha C. Anamala, Mitchell D. Thielen, Anapaula Garcia, Volha Liaudanskaya   +6 more
wiley   +1 more source

Development of a Synthetic Hydrogel to Foster Microvascularization of an Endometriosis Microphysiological System

Advanced Healthcare Materials, EarlyView.
ABSTRACT The ascent of novel alternative methods in drug development spotlights the dual needs for improved biological fidelity to in vivo, along with reproducibility, especially in regulatory applications. The need for pre‐clinical models of patient‐derived endometriosis lesions motivates the development of a vascularizable, completely synthetic ...
Lauren Pruett, Laura Bahlmann, Ryan Ogi, Angela Jiao, Priyatanu Roy, Matthew Johnson, David Trumper, Linda Griffith   +7 more
wiley   +1 more source

Punching shear capacity of expanded polystyrene (EPS) lightweight concrete flat slabs without shear reinforcement

Advances in Mechanical Engineering, 2023
This work presents an experimental and theoretical study on the punching shear behavior of Lightweight Concrete Slabs. Lightweight obtained using Expanded polystyrene (EPS) beads as partial coarse aggregate’s replacement, without adding supplementary ...
Faris Rashied Ahmed
doaj   +1 more source

Comparison of gurson and lemaitre model in the context of blanking simulation of a high strength steel [PDF]

, 2017
The process of blanking takes place in a short band with high accumulated strain undergoing various stress triaxialities. Enhanced implementations for shear and compressive loads of Gurson’s and Lemaitre’s model are directly compared for the same ...
Clausmeyer, Till, Gutknecht, Florian, Isik, Kerim, Tekkaya, Erman   +3 more
core  

Copolymers of Poly(Butylene Trans‐1,4‐Cyclohexanedicarboxylate)/Pripol as New Biomaterial Platform for Small Diameter Vascular Graft

Advanced Healthcare Materials, EarlyView.
Electrospun tubular scaffolds from novel PBCE‐based copolyesters and blends were designed as candidates for small‐diameter vascular grafts. They combine defect‐free architecture, blood‐compatible surfaces, and mechanical properties comparable to native vessels.
Edoardo Bondi, Gabriele Obino, Giulia Guidotti, Alberto Sensini, Martijn van Griensven, Antonio Junior Lepedda, Nadia Lotti, Lorenzo Moroni   +7 more
wiley   +1 more source

Structural Performance of Reinforced Concrete Flat Plate Buildings Subjected to Fire [PDF]

, 2012
El siguiente artículo se propone estudiar la poesía de Luis Hernández a partir de los problemas que surgen al intentar estudiar su obra reunida. Antes que ser valorada como una poesía “inacabada”, la deliberada asistematicidad de su poética debe ser ...
RC Elstner, A Ghaffar, S Guandalini, TZ Harmathy, Z Huang, J Lee, L Lim, J Lubliner, PJ Moss, A Muttoni, MF Ruiz, Y Tian, PA Vermeer   +12 more
core   +3 more sources

Microengineered Gradient Hydrogels for Mechanobiology

Advanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong, Deepu Ashok, Anna Waterhouse, Marcela M. M. Bilek, Daniele Vigolo   +4 more
wiley   +1 more source

Punching shear resistance of reinforced concrete footings: evaluation of design codes

Revista IBRACON de Estruturas e Materiais, 2018
Punching is a possible failure mode for slender footings and it may lead a structure to ruin through progressive collapse. Although footing present different geometric characteristics, their punching shear design is based on the empirical methods used ...
D. F. A. SANTOS, A. F. LIMA NETO, M. P. FERREIRA   +2 more
doaj   +2 more sources