Results 131 to 140 of about 22,214 (295)
针刺研究, 1993 The experimental arrhythmic model was made with Aconitin in rabbits,The Ne-iguan(PC6)point was punctured to observe the influence on recovering time ofarrhythmia.After the curative effect of puncturing Neiguan(P6)was confirmed,Ca(2+)in the Quze(PC3)point
Miao Wenfang Guo Yi Zhang Yanjun Xu Tangping。(Tianjin College of Tarditional Chinese Medicine +1 more
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Advanced Science, EarlyView.Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu +12 more
wiley +1 more source
Adipocyte‐Derived Leptolin Enhances Energy Expenditure and Prevents Obesity
Advanced Science, EarlyView.We identified a novel adipokine, which we named leptolin. In humans, leptolin levels in white adipose tissue were positively correlated with exercise and negatively associated with body mass index. We observed elevated leptolin in serum from athletes and lower leptolin in serum from obese individuals.
Jiarui Liu +17 more
wiley +1 more source
Advanced Science, EarlyView.FGF13 is upregulated in DRG neurons of PIPNP model mice. DRG neuron‐specific knockout of FGF13 ameliorates PIPNP symptoms. Mechanistically, FGF13 potentiates microtubule detyrosination by promoting VASH1 binding to microtubules. FGF13 knockout suppresses VASH1‐mediated microtubule detyrosination and promotes α‐tubulin tyrosination.
Yiming Dong +10 more
wiley +1 more source
Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy
Advanced Science, EarlyView.Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee +11 more
wiley +1 more source
Advanced Science, EarlyView.Multidrug‐resistant Vibrio infections are rising rapidly and threaten coastal populations worldwide. This study introduces D‐zp37, a chirality‐engineered antimicrobial peptide with exceptional potency against resistant Vibrio species. D‐zp37 kills planktonic cells, blocks mixed‐species biofilms, disrupts essential bacterial stress responses, and shows ...
Ping Zeng +11 more
wiley +1 more source
Advanced Science, EarlyView.Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong +24 more
wiley +1 more source
Scalp acupuncture targets for neurological disorders：evidence from neuroimaging studies （part 1）
针刺研究ObjectiveScalp acupuncture is a unique acupuncture method developed based on brain functional and pathophysiological knowledge. In past decades， there has been significant development in the understanding of the brain pathology of many neurological ...
ZHANG Bin-long +6 more
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针刺研究, 1998 This study used a method of injecting receptor blocking agants into ventricles of rabbit's brain to observe the effect of electroacupuncture and blood-letting puncturing at the twelve jing points of forepaws on rabbit's rheoencephalogram and to discuss ...
Zhou Zhiliang
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