Results 91 to 100 of about 2,738 (165)

Pomegranate Peel Extract Microemulsions for Skin Delivery: Insights into Drug Release, Skin Permeation and UV Protection

Cosmetics
Pomegranate peel, an abundant agro-industrial by-product, represents a sustainable source of bioactive polyphenols, particularly punicalagin, which has been associated with antioxidant and photoprotective potential.
Nataša Bubić Pajić, Teodora Trninić, Darija Knežević Ratković, Vesna Antunović, Katarina Šavikin, Jelena Živković, Ranko Škrbić   +6 more
doaj   +1 more source

Computational investigations of potential inhibitors of monkeypox virus envelope protein E8 through molecular docking and molecular dynamics simulations

Scientific Reports
The World Health Organization (WHO) has declared the monkeypox outbreak a public health emergency, as there is no specific therapeutics for monkeypox virus (MPXV) disease. This study focused on docking various commercial drugs and plant-derived compounds
Rohit Das, Anil Bhattarai, Rohit Karn, Buddhiman Tamang   +3 more
doaj   +1 more source

Cognition enhancement of Punicalagin following intracerebroventricular injection of Aβ (25-35) model of mice: Cognition enhancement of Punicalagin

International Journal of Biomedical and Advance Research, 2018
The hallmark in the pathology of Alzheimer disease is the deposition of amyloid plaques throughout the brain which lead to the deterioration of neuronal function and eventually they die. This damage spreads to hippocampus, region responsible for forming memories. This will ultimately lead to impairment in cognition.
Ittiyavirah, Sibi P, Raju, Rakhi
openaire   +1 more source

Punicalagin Attenuates LPS-Induced Inflammation and ROS Production in Microglia by Inhibiting the MAPK/NF-κB Signaling Pathway and NLRP3 Inflammasome Activation

Journal of Inflammation Research, 2022
Jung Lo,1,2 Ching-Chih Liu,3,4 Yueh-Shan Li,3 Po-Yen Lee,3,5 Po-Len Liu,6 Pei-Chang Wu,1,2 Tzu-Chieh Lin,7 Chi-Shuo Chen,8 Chien-Chih Chiu,9 Yu-Hung Lai,3,5,10 Yo-Chen Chang,3,5,10 Hsin-En Wu,3 Yuan-Ru Chen,3 Yu-Kai Huang,3,11 Shu-Pin Huang,1,12– 14 Shu ...
Lo J, Liu CC, Li YS, Lee PY, Liu PL, Wu PC, Lin TC, Chen CS, Chiu CC, Lai YH, Chang YC, Wu HE, Chen YR, Huang YK, Huang SP, Wang SC, Li CY   +16 more
doaj  

Analysis of Osteosarcoma Cell Lines and Patient Tissue Using a 3D In Vivo Tumor Model—Possible Effects of Punicalagin

Organoids
Osteosarcomas are the most common primary malignant bone tumors and mostly affect children, adolescents, and young adults. Despite current treatment options such as surgery and polychemotherapy, the survival of patients with metastatic disease remains ...
Anna Rebecca Dorn, Sara Neff, Sophia Hupp, Melissa Engelhardt, Eric Pion, Ulrich Lenze, Carolin Knebel, Anna Duprée, Simone Schewe, Markus Weber, Christian Wulbrand, Axel Hillmann, Florian Weber, Phillip Clarke, Philipp Kainz, Thiha Aung, Silke Haerteis   +16 more
doaj   +1 more source

Anticancer effects of Punicalagin

Haydarpasa Numune Training and Research Hospital Medical Journal, 2021
openaire   +1 more source

The polyphenolic compound punicalagin protects skin fibroblasts from UVA radiation oxidative damage

Current Research in Pharmacology and Drug Discovery
Polyphenols are a class of natural compounds that act as antioxidants, neutralising harmful free radicals that would damage cells and increase the risk of diseases such as cancer, diabetes and heart disease.
Giada Bianchetti, Patrizia Bottoni, Giuseppe Tringali, Giuseppe Maulucci, Elisabetta Tabolacci, Maria Elisabetta Clementi   +5 more
doaj   +1 more source

Study on the Effects of Tannase on the De Astringency of Pomegranate Juice

Foods
Reducing the punicalagin content is an effective strategy for eliminating the astringency of pomegranate juice. In this study, pomegranate juice was used as the raw material, and tannase was applied to convert punicalagin into ellagic acid and gallic ...
Guida Zhu, Longwen Wang, Han Wang, Zihan Chen, Xue Li, Yi Ji, Jing Yu, Ping Song   +7 more
doaj   +1 more source

Blockade of PAR2 Signaling by Punicalagin as a Therapeutic Strategy for Atopic Dermatitis

International Journal of Molecular Sciences
Atopic dermatitis is a chronic inflammatory skin disorder characterized by persistent inflammation and severe pruritus. Current anti-inflammatory agents carry risks of long-term adverse effects, while antihistamines provide limited relief of pruritus.
Hyejin Jeon, Yohan Seo, Wook-Joo Lee, Yunkyung Heo, Won-Sik Shim, Wan Namkung   +5 more
openaire   +3 more sources

Helicase A determines the transcription program of T_H17 lineage differentiation and autoimmunity. [PDF]

Sci Adv
Su Y, Jiao A, Zhang X, Xu Y, Ping H, Zhu K, Wang Q, Yuan N, Gao Y, Ju B, Ding R, Wang N, He L, Lei L, Zhao Y, Zhang M, Zhang B.   +16 more
europepmc   +1 more source