Results 31 to 40 of about 69,155 (267)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

open access: yesFEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli   +3 more
wiley   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

مفهوم التعزير في الفقه السياسي دراسة مقارنة بمفهوم التقنين

open access: yesİlahiyat Akademi, 2022
يعد مفهوم التعزير من المفاهيم الأصيلة في الفقه الإسلامي؛ فالعقوبات في الشريعة الإسلامية تنقسم إلى حدود وتعازير، أما العقوبات الحديَّة فهي التي حددها الله سبحانه وتعالى، وأما العقوبات التعزيرية فهي التي تركت الشريعة الإسلامية تقديرها إلى القاضي، وللقاضي ...
Muhammer Nur Hamden
doaj   +1 more source

Profound Leadership Strategies: Transcending the Leadership Crisis in the Age of Artificial Intelligence

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT This article examines the evolving role of organizational leadership amidst the rapid advancements in artificial intelligence (AI). It explores a broadly experienced and documented crisis in leadership, due in part to the disruptive nature of AI and emerging technology.
Rachel Wlodarsky, Davin Carr Chellman
wiley   +1 more source

LAWFUL BEHAVIOUR AS A SPECIAL TYPE OF THE PERSON’S SOCIAL BEHAVIOUR OF

open access: yesВестник Кемеровского государственного университета, 2014
The paper addresses the relation between social and lawful behavior of the person as a generic andspecific element, revealing their general and distinctive signs.
A. S. Morozov
doaj  

Factors associated with late diagnosis of breast cancer among women in Botswana

open access: yesAfrican Journal of Primary Health Care & Family Medicine
Background: Breast cancer is a public health issue in Botswana. Associations of patient-level factors with late breast cancer diagnosis are not well understood. This may explain why there are many cases of late diagnosis.
Punishment P. Chibatamoto   +2 more
doaj   +1 more source

Thinking about Punishment across Space and Time

open access: yesKriminologijos studijos, 2014
This short essay shows why the customary two-categories of punishment theories (retributive theories and consequentialist theories) should be increased to three to include a-normative theory and how that would aid understanding of differences in ...
MICHAEL TONRY
doaj   +1 more source

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem   +17 more
wiley   +1 more source

Narratives from the margins of the state: resisting the politics of exceptionality in the Comuna 13

open access: yesOñati Socio-Legal Series, 2018
This article questions the implementation of the “state of exception” in marginal urban areas of Colombia. In so doing, it takes as a case study the military operations carried out in 2002, in Comuna 13, an urban district of Medellín.
Gustavo Rojas-Páez
doaj  

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