Results 91 to 100 of about 103,266 (267)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

THE USE OF ICT IN QUALITY EDUCATION MANAGEMENT IN PRIVATE GYMNASIUMS

Ìнформаційні технології в освіті, 2012
The article deals with the peculiarities of the use of information and communication technologies (ICT) in the process of the quality education management in private gynasiums.
I.V. Plish
doaj  

Comparison of pupil size in patients of migraine with photophobia versus normal subjects and correlation of the pupil size to severity of headache

Indian Journal of Ophthalmology
Purpose: To compare the pupil size of patients having migraine with photophobia versus normal subjects and to correlate the pupil size to the severity of headache. Methods: This was a prospective case–control study.
Ruby Moharana, Kiran B Bhandari
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Universal, school-based, interventions to improve emotional outcomes in children and young people: a systematic review and meta-analysis

Frontiers in Child and Adolescent Psychiatry
IntroductionThere is debate into the impact of universal, school-based interventions to improve emotional outcomes. Previous reviews have only focused on anxiety and depression symptoms, omitting broader internalising symptoms, nor include the ...
Daniel Hayes, Daniel Hayes, Emre Deniz, Kirsty Nisbet, Abigail Thompson, Anna March, Anna March, Carla Mason, Joao Santos, Rosie Mansfield, Emma Ashworth, Bettina Moltrect, Bettina Moltrect, Shaun Liverpool, Hannah Merrick, Jan Boehnke, Neil Humphrey, Paul Stallard, Praveetha Patalay, Praveetha Patalay, Jessica Deighton, Jessica Deighton   +21 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Pathways to School Reentry for Children and Young People with a Medical or Mental Health Condition: An International Delphi Study

Continuity in Education
Prolonged school absences among children and young people hospitalized due to medical or mental health conditions can significantly disrupt their social and academic development.
Michele Capurso, Valentina Moracci, Simone Borsci   +2 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source