Results 151 to 160 of about 103,266 (267)

Partial pupil-sparing third nerve palsy as a manifestation of cerebral toxoplasmosis in an HIV-positive patient: A case report. [PDF]

Am J Ophthalmol Case Rep
Aljohani HA, Alzahrani AS, Alrashid AS, Tuwair I.   +3 more
europepmc   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Assessing Pupil Light Reflex Metrics in Glaucoma: Insights from a Systematic Review and Meta-Analysis. [PDF]

Ophthalmol Sci
Moniritilaki M, Wagner P, Khuu SK.
europepmc   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Webcam-Based Pain Measurement Using Pupillary Diameter. [PDF]

Sensors (Basel)
Shamantseva N, Polyakov A, Lyakhovetskii V, Bystrova M, Sakun I, Ananyev S, Gerasimenko Y, Moshonkina T.   +7 more
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

THE TABETIC PUPIL [PDF]

British Journal of Ophthalmology, 1941
openaire   +4 more sources

Task-Evoked Pupillary Dynamics Are Altered in Post-COVID Syndrome. [PDF]

Med Sci (Basel)
Smit A, Fleischmann P, Knauer TS, Mardin CY, Michelson G, Zott J, Güttes M, Sarmiento H, Ilgner M, Jakobi M, Rech J, Hohberger B.   +11 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Investigating the test-retest reliability and behavioral correlates of pupil responses in the n-back task. [PDF]

Sci Rep
Bényei GL, Pajkossy P.
europepmc   +1 more source