Results 151 to 160 of about 524,807 (298)

National pupil projections: future trends in pupil numbers [PDF]

, 2013
Cotzias, Eleanor
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Management of ocular aberration and convergence excess after laser‐assisted in situ keratomileusis with vision therapy

Eye & ENT Research
Prithwis Manna, Sourav Karmakar, Animesh Mondal, Puja Sarbajna, Rikta Paul, Mahesh Mudi   +5 more
doaj   +1 more source

Pupil-based arousal self-regulation: impact on physiological and affective responses to emotional stimuli. [PDF]

Transl Psychiatry
Imhof J, Raschle NM, Wenderoth N, Meissner SN.   +3 more
europepmc   +1 more source

National pupil projections : future trends in pupil numbers [PDF]

, 2012
Tuddenham, Fay
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Attenuated pupillary response during visual search in preclinical Alzheimer's disease. [PDF]

Alzheimers Dement
Festa EK, Heindel WC, Marangi CA, Escobedo B, Galasko DR, Salmon DP, Zou J, Jacobs DM.   +7 more
europepmc   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Anne-Marie Chartier, L’école et l’écriture obligatoire

Strenae, 2023
Hélène Weis
doaj   +1 more source