Results 91 to 100 of about 3,239,802 (389)

Implementation of Hough Transform and Artificial Neural Network for Eye Fatigue Detection in Mobile Phone Usage

Engineering Proceedings
The eye, in a dominant sense, can suffer disorders, such as myopia or nearsightedness, because of VDU radiation exposure. One symptom which is often caused by excessive use of VDU is eye strain.
Alun Sujjada, Rizki Rahmatulloh, Suganda, Andrean Maulana   +3 more
doaj   +1 more source

Evaluation of Cholinergic Deficiency in Preclinical Alzheimer’s Disease Using Pupillometry

Journal of Ophthalmology, 2017
Cortical cholinergic deficiency is prominent in Alzheimer’s disease (AD), and published findings of diminished pupil flash response in AD suggest that this deficiency may extend to the visual cortical areas and anterior eye.
Shaun Frost, Liam Robinson, Christopher C. Rowe, David Ames, Colin L. Masters, Kevin Taddei, Stephanie R. Rainey-Smith, Ralph N. Martins, Yogesan Kanagasingam   +8 more
doaj   +1 more source

The comparison of optic pathway injury elements at brain concussion and light contusion in dynamics of acute period

Ukrainian Neurosurgical Journal, 2010
Brain concussion (BC) is characterized mainly by damage of subcortical brain structures (chiasma) and extrastrial zone of optic pathway, oculomotor nerve and afferent part of pupil pathway.
N. M. Moyseenko
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Individual differences in belief updating and phasic arousal are related to psychosis proneness

Communications Psychology
Many decisions entail the updating of beliefs about the state of the environment by accumulating noisy sensory evidence. This form of probabilistic reasoning may go awry in psychosis.
Peter R. Murphy, Katarina Krkovic, Gina Monov, Natalia Kudlek, Tania Lincoln, Tobias H. Donner   +5 more
doaj   +1 more source

Differences in selected coordinaton abilities between pupils with communication ability disorder and able-bodied pupils

Acta Facultatis Educationis Physicae Universitatis Comenianae, 2018
Abstract The aim of the study was to analyse and compare the level of selected coordination abilities of pupils with communication ability disorder (CAD) and able-bodied pupils in the same age category. Two groups of participants were recruited for the study: (1) pupils attending special elementary school for children with CAD (n = 17; 5
Stanislav Kraček, Dagmar Nemček, Petra Kurková, Wioletta Lubkowska, Šimon Tomáš   +4 more
openaire   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Severe Anisocoria after Oral Surgery under General Anesthesia

International Journal of Medical Sciences, 2010
Introduction. Anisocoria indicates a difference in pupil diameter. Etiologies of this clinical manifestation usually include systemic causes as neurological or vascular disorders, and local causes as congenital iris disorders and pharmacological effects ...
Francesco Inchingolo, Marco Tatullo, Fabio M. Abenavoli, Massimo Marrelli, Alessio D. Inchingolo, Bruno Villabruna, Angelo M. Inchingolo, Gianna Dipalma
doaj