Results 71 to 80 of about 29,156 (297)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

The pupil reaction to light in patients with affective disorders

open access: yes, 2010
The purpose of the present study is the evaluation of the changes in the size and movement of the pupil in patients with major depression with melancholic features and in patients with bipolar disorder type I using pupillometry in comparison with normal ...
Νάκου, Μαρία, Nakou, Maria
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

A Pediatric Case of Benign Episodic Unilateral Mydriasis with Clinical Characteristics Resembling Tadpole Pupil

open access: yes, 2022
Benign episodic unilateral mydriasis is an episodic disturbance with dilatation of the entire pupil, often lasting for hours. It occurs most frequently in women aged between 20 and 50 years and is closely associated with migraines.
Hansen, Jonas Kjeldbjerg   +2 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Pupil Disorders, Is Pharmacological Testing Necessary?

open access: yes, 2010
Disorders of the iris sphincter that may require pharmacologic testing cholinergic super-sensitivity vs. under-sensitivity: When evaluating an anisocoria that increases in bright light and decreases in dim light, attention usually shifts toward the ...
Randy H. Kardon; Jonathan D. Trobe
core  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

How to test for a relative afferent pupillary defect (RAPD)

open access: yesCommunity Eye Health Journal, 2012
The 'swinging light test' is used to detect a relative afferent pupil defect (RAPD): a means of detecting differences between the two eyes in how they respond to a light shone in one eye at a time.
David C Broadway
doaj  

A study on the relationship between teachers and students with special needs

open access: yesINFAD, 2014
The impact of the teacher-student relationship on the child’s development proves to be particularly important in the first years of scholarization. Such impact is even higher in students with atypical development.
Laura Elvira Prino   +3 more
doaj   +1 more source

Temporal, spatial and adaptation characteristics of melanopsin inputs to the human pupil light reflex

open access: yes, 2016
This thesis advanced understanding of the timing, spatial and adaptation properties of the human pupil light reflex (PLR). It developed new functional measures of the eye's melanopsin cells, which regulate circadian rhythms and pupil size, and are ...
Joyce, Daniel S.
core  

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