Results 91 to 100 of about 29,156 (297)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

The diagnostic significance of pupillary reflex pathways: insights from classical examination and advanced pupillometry

open access: yesFrontiers in Neuroscience
Background/objectivesThe pupil, a dynamic ocular structure, serves as a critical indicator of neurological and ophthalmological function. This interdisciplinary review explores the anatomical, physiological, and pathological aspects of pupillary reflexes
Łukasz Lisowski   +5 more
doaj   +1 more source

Posture disorders and their causes in rural schools pupils

open access: yesSocial welfare : interdisciplinary approach, 2016
The aim of the research is to identify the particularities of pupils’ body posture in the rural schools of Šiauliai region. Particularities of pupils’ body posture were screened using Adams forward bend test. It was found out that faulty body posture (lesion of skeleton-muscle system and asymmetry of innervations) is common to the largest part of ...
Liuda Radzevičienė,   +1 more
openaire   +3 more sources

Problematic pupil from the teacher's perspective [PDF]

open access: yes, 2018
Title: Problematic pupil from the teacher's perspective Author: Bc. et Bc. Nikola Sodomková Supervisor: PhDr. Veronika Pavlas Martanová, Ph.D. Department: Psychology Abstract The diploma thesis deals with problematic pupils in elementary school. The main
Sodomková, Nikola
core  

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Severe Anisocoria after Oral Surgery under General Anesthesia

open access: yesInternational Journal of Medical Sciences, 2010
Introduction. Anisocoria indicates a difference in pupil diameter. Etiologies of this clinical manifestation usually include systemic causes as neurological or vascular disorders, and local causes as congenital iris disorders and pharmacological effects ...
Francesco Inchingolo, Marco Tatullo, Fabio M. Abenavoli, Massimo Marrelli, Alessio D. Inchingolo, Bruno Villabruna, Angelo M. Inchingolo, Gianna Dipalma
doaj  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Pupil diameter and Behavioral Responsiveness in Disorders of Consciousness

open access: yes, 2019
The clinical diagnosis of consciousness is mainly based on bedside observation of the patient's responses using standardized neurobehavioral scales. By definition, it is common to observe vigilance fluctuation in patients in minimally conscious state ...
Laureys, Steven   +3 more
core  

Constructing Stage-Environment Fit: Early Adolescents' Psychological Development and their Attitudes Towards School in English Middle and Secondary School Environments

open access: yes, 2010
This longitudinal multiple methods study used an ethnographic approach to examine the development of early adolescents’ psychology during pubertal and school transitions.

core   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

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