Results 81 to 90 of about 29,156 (297)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Migraine and pupillary dysfunction, the presentation of episodic anisocoria in a patient with migraine headache [PDF]

Düşünen Adam Psikiyatri ve Nörolojik Bilimler Dergisi, 2011
Anisocoria is pupil’s asymmetrical reaction to light. The etiology behind anisocoria is mostly due to disorders affecting the sympathetic and parasympathetic pathways.
Nilufer Kale, Mesude Ozerden, Nazan Karagoz Sakalli, Dursun Kirbas   +3 more
doaj  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Implementation of Hough Transform and Artificial Neural Network for Eye Fatigue Detection in Mobile Phone Usage

Engineering Proceedings
The eye, in a dominant sense, can suffer disorders, such as myopia or nearsightedness, because of VDU radiation exposure. One symptom which is often caused by excessive use of VDU is eye strain.
Alun Sujjada, Rizki Rahmatulloh, Suganda, Andrean Maulana   +3 more
doaj   +1 more source

Evaluation of Cholinergic Deficiency in Preclinical Alzheimer’s Disease Using Pupillometry

Journal of Ophthalmology, 2017
Cortical cholinergic deficiency is prominent in Alzheimer’s disease (AD), and published findings of diminished pupil flash response in AD suggest that this deficiency may extend to the visual cortical areas and anterior eye.
Shaun Frost, Liam Robinson, Christopher C. Rowe, David Ames, Colin L. Masters, Kevin Taddei, Stephanie R. Rainey-Smith, Ralph N. Martins, Yogesan Kanagasingam   +8 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

The comparison of optic pathway injury elements at brain concussion and light contusion in dynamics of acute period

Ukrainian Neurosurgical Journal, 2010
Brain concussion (BC) is characterized mainly by damage of subcortical brain structures (chiasma) and extrastrial zone of optic pathway, oculomotor nerve and afferent part of pupil pathway.
N. M. Moyseenko
doaj   +1 more source

Identifying Vision Disorders Using Pupil Color Analysis [PDF]

, 2009
Amblyopia is a neurological vision disorder that studies show affects two to five percent of the population. Current methods of treatment produce the best visual outcome if the condition is identified early in the patient's life.
Clark, Patrick G.
core  

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Individual differences in belief updating and phasic arousal are related to psychosis proneness

Communications Psychology
Many decisions entail the updating of beliefs about the state of the environment by accumulating noisy sensory evidence. This form of probabilistic reasoning may go awry in psychosis.
Peter R. Murphy, Katarina Krkovic, Gina Monov, Natalia Kudlek, Tania Lincoln, Tobias H. Donner   +5 more
doaj   +1 more source