Results 101 to 110 of about 3,239,802 (389)

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Emotion, working memory, and cognitive control in patients with first-onset and previously untreated minor depressive disorders

open access: yesJournal of International Medical Research, 2016
Objective To explore working memory and the ability to process different emotional stimuli in patients with first-onset and untreated minor (mild or moderate) depression.
Mi Li   +5 more
semanticscholar   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Challenging behaviour in school – special education teachers’ perceptions

open access: yesSpecialusis Ugdymas, 2016
This article explores the challenges that special education teachers encounter during their daily work in Finnish schools. The main focus is in those challenges which cause worry among teachers, especially aggressive behavior in class rooms and school ...
Pilvi Hämeenaho
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Inspecting independent special schools : section 162A independent school inspection guidance [PDF]

open access: yes, 2011
"This document provides guidance to assist inspectors in carrying out section 162A inspections of independent schools which cater wholly or mainly for pupils with special educational needs and/or disabilities" -- front ...

core  

Combining computer game-based behavioural experiments with high-density EEG and infrared gaze tracking [PDF]

open access: yes, 2010
Rigorous, quantitative examination of therapeutic techniques anecdotally reported to have been successful in people with autism who lack communicative speech will help guide basic science toward a more complete characterisation of the cognitive profile ...
Belmonte, MK, Yoder, KJ
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Evaluating multimodal physiological signals for fear detection: relative utility of pupillometry, heart rate, and EEG

open access: yesFrontiers in Human Neuroscience
IntroductionFear is a fundamental emotion essential for survival; however, excessive fear can lead to anxiety disorders and other adverse consequences. Monitoring fear states is crucial for timely intervention and improved mental well-being.
Yuki Ebato   +11 more
doaj   +1 more source

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