Results 61 to 70 of about 137,513 (347)

Industrial market segmentation by the structure of the purchasing process [PDF]

open access: yesIndustrial Marketing Management, 1980
Abstract This article presents a methodology for segmenting industrial markets on the basis of functional involvement in phases of the purchasing decision process. A decision matrix is developed as a structured measurement instrument to collect information about the composition of decision making units within target firms.
Choffray, Jean-Marie, Lilien, Gary L.
openaire   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Harmonized Purchase Order Process at Computacenter AG

open access: yes, 2023
Currently there are various systems and processes in place at Computacenter AG for managing different business functions across different departments, but some of these processes are manual or lack standardization. There is no single process which covers
Mägli, Jonas   +3 more
core  

Influence of basic demographic characteristics of children consumers on family travel purchase [PDF]

open access: yesMarketing (Beograd. 1991), 2017
During the last two decades, researchers in the field of tourism and marketing direct increasing attention towards the process of making purchasing decisions within the family.
Tomić Slavica, Leković Ksenija
doaj  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

TINDAK TUTUR DALAM PROSES JUAL BELI DI PASAR TRADISIONAL SURAKARTA

open access: yesPrasasti: Journal of Linguistics, 2016
The objectives of this research are: to describe the forms of speech acts and to show the most dominant speech act and the reasons of its use; and to describe and define the politeness principle found in the the goods sale and purchase process at ...
Ririn Linda Tunggal Sari   +2 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Green Purchase Behavior: The Effectiveness of Sociodemographic Variables for Explaining Green Purchases in Emerging Market

open access: yesSustainability, 2020
Environmental degradation is a serious problem in modern civilization as it causes changes in consumer behavior towards ecologically responsible purchasing.
L. Witek, W. Kuźniar
semanticscholar   +1 more source

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