Results 81 to 90 of about 10,885,424 (303)

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

A Flexible Class of Purchase Incidence Models [PDF]

open access: yes
Purchase incidence models estimated on household scanner panel data typically assume the household's decision interval to be one week. However, it is well known in the econometrics literature that discrete-time models are highly sensitive to the assumed ...
Trichy Krishnan, Seethu Seetharaman
core  

Annual power purchase strategy considering multi-period sequential trading risks

open access: yesZhongguo dianli
As a result of the sequential trading process, the decision-making of power purchasers is intercoupled across different trading periods. Therefore, power purchasers need to consider the trading risks in each period comprehensively and make power purchase
Guoxin LIN   +4 more
doaj   +1 more source

When a promotion is denied: the effects of decision stage on perceptions of promotion and price fairness

open access: yesEconomic and Business Review, 2011
Marketers frequently use promotions to enhance sales and increase consumers’ perceptions of value. However, most promotions usually come with restrictions, such as time expiration, quantity or product model restriction, etc.
Monika Kukar-Kinney   +2 more
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Tweenagers influence on purchase decision-making: A gender role orientation (GRO) perspective [PDF]

open access: yes, 2005
This study examines the influence of children aged 10-12 at different stages of purchase decisions and the effect of gender role orientation on a child's involvement.
Tinson, Julie, Nancarrow, Clive
core  

Decision-Making Within Technical Due Diligence for Land Development Using Machine Learning Algorithms

open access: yesApplied Sciences
In the decision-making process related to the purchase of land properties intended for construction investments, the Technical Due Diligence (TDD) process plays a key role.
Elżbieta Radziszewska-Zielina   +2 more
doaj   +1 more source

UNPACKING THE ROLE OF REFERENCE GROUPS IN SHAPING CONSUMER PURCHASE INTENTIONS WITHIN THE AUTOMOTIVE SECTOR [PDF]

open access: yesMSA-Management Sciences Journal
The purpose of this study is to investigate the influence of reference groups on the purchase intentions of Egyptian Automotive customers. The design and methodology of this research involve a survey questionnaire to collect data from a sample of ...
Yasser Halim, Mohamed ElDeeb
doaj   +1 more source

The family purchasing process of broadband internet in Australia

open access: yesInternational Journal of Technology Marketing, 2006
This study investigates the purchasing process of broadband internet in Australian families. The study was motivated by the question of why broadband adoption rate is low in Australia. Broadband as a telecommunication service is used collectively by family members. Therefore, we interviewed 15 families.
Sandra Ahn, Shanton Chang, Heejin Lee
openaire   +3 more sources

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