Results 91 to 100 of about 10,885,424 (303)

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

THE INFLUENCE OF CONTENT MARKETING ON AZLOE'S PRODUCT PURCHASE DECISIONS PROCESS

open access: yesJournal of Management Small and Medium Enterprises (SME's)
This study aims to analyze the effect of content marketing on the @azloeofficial TikTok on Azloe’s product purchasing decisions through TikTok Shop. This research uses a descriptive verification analysis method.
Shafa Syahida Islamidina   +2 more
doaj   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

Consumer Procrastination and Purchase Delay. [PDF]

open access: yes
Les recherches concentrées sur le report d'achat ont proposé de nombreux facteurs explicatifs aussi bien situationnels qu'individuels. Ce papier propose de conceptualiser la Procrastination comme facteur individuel qui oriente les individus à reporter ...
Darpy, Denis
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"Emotions That Influence Purchase Decisions And Their Electronic Processing " [PDF]

open access: yesAnnales Universitatis Apulensis Series Oeconomica, 2009
Recent studies have shown that most of our purchasing choices and decisions are the result of a careful analysis of the advantages and disadvantages and of affective and emotional aspects. Psychological literature recognizes that the emotional conditions are always present and influence every stage of decision-making in purchasing process.
openaire   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

THE ROLE OF SOCIAL MEDIA IN CUSTOMER PURCHASE DECISIONS THROUGH MARKETING MANAGEMENT AMONG TIKTOK SHOP USERS IN INDONESIA (2025)

open access: yesManajemen Bisnis
This study aims to describe the condition of social media, marketing management, and purchase decision, analyze the influence of social media on purchase decision, analyze the influence of social media on marketing management, analyze the influence of ...
Irfan Irfan
doaj   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Mooralla and Kenilworth Estates [cartographic material] : plan.

open access: yes, 1910
Sales plan for land in Cavendish region, Victoria. Relief shown by hachures. Includes locality map.; Includes text and ill. on verso.; At head of panel title: E.R.
Lands Purchase and Management Board of Victoria.
core  

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