Results 91 to 100 of about 137,513 (347)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
The influence of creative packaging design on customer motivation to process and purchase decisions
Journal of business research, 2022 Paurav Shukla +2 more
semanticscholar +1 more source
Applied SciencesIn the decision-making process related to the purchase of land properties intended for construction investments, the Technical Due Diligence (TDD) process plays a key role.
Elżbieta Radziszewska-Zielina +2 more
doaj +1 more source
UNPACKING THE ROLE OF REFERENCE GROUPS IN SHAPING CONSUMER PURCHASE INTENTIONS WITHIN THE AUTOMOTIVE SECTOR [PDF]
MSA-Management Sciences JournalThe purpose of this study is to investigate the influence of reference groups on the purchase intentions of Egyptian Automotive customers. The design and methodology of this research involve a survey questionnaire to collect data from a sample of ...
Yasser Halim, Mohamed ElDeeb
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Involvement and use of multiple search channels in the automobile purchase process [PDF]
In this study we investigate the relationship between involvement and use of multiple search channels in the case of pre-purchase information search for automobiles.
Frank J. van Rijnsoever +2 more
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The family purchasing process of broadband internet in Australia
International Journal of Technology Marketing, 2006 This study investigates the purchasing process of broadband internet in Australian families. The study was motivated by the question of why broadband adoption rate is low in Australia. Broadband as a telecommunication service is used collectively by family members. Therefore, we interviewed 15 families.
Sandra Ahn, Shanton Chang, Heejin Lee
openaire +3 more sources
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Influential factors of agricultural chemical purchase
, 1997 The purpose of this research was to identify the key factors in the decision making process that motivate end users to purchase a particular brand of agricultural chemical within a designated product category.
Pedersen, Daniel +2 more
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