Results 31 to 40 of about 215,424 (291)

Guidance on how to balance the purchasing environment and processes to save resources - a validity examination of a holistic model

Cogent Business & Management
Despite the evolution of purchasing operations over many years, a comprehensive perspective is lacking in practice, leading to inefficiencies. This study aims to validate a model designed to guide how to balance the purchasing environment.
Maria M. Wittinger, Krisztina Demeter
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

The Mediating Effect of Herd Behavior and Brand Attitude towards the Impact of Spokesman Credibility, Source Fit, and Online Word-of-Mouth on Purchase Intention [PDF]

, 2023
Bo-chiuan Su, Li‐Wei Wu, Lin Hong-xi, Chieh-An Lin   +3 more
openalex   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

A review of human factors and infusion pumps: lessons for procurement

Frontiers in Digital Health
Integrating advanced technologies like medical devices in healthcare is crucial for addressing critical challenges, but patient safety must remain the top priority. In modern clinical settings, medical devices, such as infusion devices used to administer
Laura Herrero, Marina Cano, Raj Ratwani, Laura Sánchez, Blanca Sánchez, Ramón Sancibrián, Galo Peralta   +6 more
doaj   +1 more source

DIRECTIONS OF INCREASE OF EFFICIENCY OF FUNCTIONING OF THE INSTITUTION OF BANKRUPTCY

Модернизация, инновация, развитие, 2016
This article presents a synthesis of the experience of foreign government and corporate procurement management. Set out key aspects of the organization of procurement for government and corporate needs, disclosed issues of centralization and ...
Antonina Nikolaevna Ryakhovskaya
doaj   +1 more source

Factors Influencing Online Purchase Intention of Shopee’s Consumers in Malaysia [PDF]

, 2021
Lee Jing Ru, Tan Owee Kowang, Choi Sang Long, Sook-Fun Fong, Goh Chin Fei   +4 more
openalex   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Case studies for implementing MCDA for tender and purchasing decisions in hospitals in Indonesia and Thailand

Journal of Pharmaceutical Policy and Practice, 2021
Background A multi-criteria decision analysis (MCDA) approach has been suggested for helping purchasers in low-and middle-income countries in an evidence-based assessment of multi-source pharmaceuticals to mitigate potential adverse consequences of price-
Anke-Peggy Holtorf, Erna Kristin, Anunchai Assamawakin, Nilawan Upakdee, Rina Indrianti, Napassorn Apinchonbancha   +5 more
doaj   +1 more source