Results 41 to 50 of about 107,549 (268)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Sistem Informasi Akuntansi Pembelian Bahan Baku untuk Proyek

ComTech, 2012
Along with the development of technology, every line of business as well as a company that specializes in a construction project requires an information system that can support the company’s operations.
Lianawati Cristian, D. Meutia
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Guidance on how to balance the purchasing environment and processes to save resources - a validity examination of a holistic model

Cogent Business & Management
Despite the evolution of purchasing operations over many years, a comprehensive perspective is lacking in practice, leading to inefficiencies. This study aims to validate a model designed to guide how to balance the purchasing environment.
Maria M. Wittinger, Krisztina Demeter
doaj   +1 more source

Evaluasi Implementasi Proyek Sistem Aplikasi Terintegrasi Persediaan, Pembelian dan Penjualan: Studi Kasus Cyber Project di PT Pura Mayungan

ComTech, 2012
In industry field, designing products that meet the criterias and expectations of the consumers is a must. PT Pura Mayungan as an industry panel company obtained a Cyber Project which required a particular project management system. In the meantime, the
Iwan Kurniawan Widjaya
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

THE INFLUENCE OF ENVIRONMENTAL AWARENESS AND GREEN MARKETING ON PURCHASING DECISIONS FOR ECO-FRIENDLY PRODUCTS THROUGH ENVIRONMENTAL KNOWLEDGE OF ECO-FRIENDLY PACKAGING CONSUMERS [PDF]

Russian Journal of Agricultural and Socio-Economic Sciences
This research aims to evaluate the influence of environmental awareness and green marketing on purchasing decisions for Eco-Friendly products through consumers' environmental knowledge about Eco-Friendly packaging.
Purwanto F.X.A., Harahap N., Khusaini M., Ciptadi G., Aminuddin M.F., Badriya N.   +5 more
doaj  

DIRECTIONS OF INCREASE OF EFFICIENCY OF FUNCTIONING OF THE INSTITUTION OF BANKRUPTCY

Модернизация, инновация, развитие, 2016
This article presents a synthesis of the experience of foreign government and corporate procurement management. Set out key aspects of the organization of procurement for government and corporate needs, disclosed issues of centralization and ...
Antonina Nikolaevna Ryakhovskaya
doaj   +1 more source