Results 31 to 40 of about 107,549 (268)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Planning model of purchasing logistics in outsourcing [PDF]

open access: yesTransport Problems, 2014
It is often the case that when preparing their offers, potential outsourcers of logistic activities do not thoroughly research all the activities that have an influence on the process of logistics.
Igor JAKOMIN, Rok KOBILICA
doaj  

A multi-criteria decision analysis (MCDA) tool for purchasing off-patent oncology medicines in Egypt

open access: yesJournal of Pharmaceutical Policy and Practice, 2022
Background Multi- criteria decision analysis (MCDA) can assist policymakers in objectively choosing between alternative therapeutic options based on multiple value attributes.
Baher Elezbawy   +12 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

A review of human factors and infusion pumps: lessons for procurement

open access: yesFrontiers in Digital Health
Integrating advanced technologies like medical devices in healthcare is crucial for addressing critical challenges, but patient safety must remain the top priority. In modern clinical settings, medical devices, such as infusion devices used to administer
Laura Herrero   +6 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

The role of procurement quality controls in procurement performance in the energy sector in Zimbabwe

open access: yesCogent Engineering, 2019
Procurement performance is a rapidly developing area of research. Many companies are trying to find tools for optimising procurement performance measures in response to turbulent business markets and for efficiently controlling their business activities.
Tinotenda Fredrick Munyimi
doaj   +1 more source

Pengembangan Aplikasi Sistem Basis Data Penjualan, Pembelian, dan Persediaan: Studi Kasus Pada PT. Speed Game

open access: yesComTech, 2011
This study aims to to perform database application development system on purchasing, sales and inventory of PT. Speed Game, a company that applies manual database system.
Honni Honni   +2 more
doaj   +1 more source

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