Results 71 to 80 of about 107,549 (268)
STRATEGIC PURCHASING IN A PROJECT- BASED COMPANY – TO CENTRALIZE OR DECENTRALIZE [PDF]
Acta Logistica, 2014 Organizations all lie on a spectrum, at one end of which are firms with complete centralization of purchasing, and at the other end are firms with complete decentralization.
Eva Donociková
doaj
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Cost management in metallurgical production
Metalurgija, 2012 Price changes in the global raw material markets significantly infl uence the economic characteristics of Czech metallurgical companies as well. This article illustrates the utilization of changeable market situation when purchasing of raw materials infl
K. Janovská +5 more
doaj
Gender Differences and Consumer Behavior of Millennials
Acta Economica et Turistica, 2017 Millennial generation is considered the largest and best educated and therefore presents challenges to marketers. This paper aims to examine the gender differences in consumer behaviour of students - generation y.
Kraljević Radojka, Filipović Zrinka
doaj +1 more source
Why Substantial Budget Reallocations Are Not and Should Not Be a Major Factor in Active Purchasing in Dutch Healthcare; Comment on “Measuring Active Purchasing in Healthcare: Analysing Reallocations of Funds Between Providers to Evaluate Purchasing Systems Performance in the Netherlands” [PDF]
International Journal of Health Policy and ManagementThis commentary discusses the study by Stadhouders et al, which analyzes budget reallocations among Dutch healthcare providers as a result of one form of active purchasing.
Fredo Schotanus
doaj +1 more source
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
Knowledge of UK Residents About Importing Puppies from EU Countries
AnimalsThe number of puppies imported to the United Kingdom (UK) from the European Union (EU) is increasing, as are concerns about the legality, welfare and potential disease risks associated with their trade. This study aimed to use an online survey to collect
Zoe Belshaw, Rowena M. A. Packer
doaj +1 more source
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source