Results 81 to 90 of about 1,148,210 (288)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

PENGARUH E-SERVICE QUALITY TERHADAP KEPUTUSAN PEMBELIAN DENGAN KEPERCAYAAN KONSUMEN SEBAGAI VARIABEL MEDIASI (Studi Kasus di Marketplace Shopee pada Online Shop “Grosir Asemka”) [PDF]

open access: yes, 2023
This research was conducted on Grosir Asemka consumers who made purchases through the Shopee marketplace, with the aim of the study to determine: the effect of e-service quality on purchasing decisions, es-service quality on consumer trust, consumer ...
Aini, Safira Nur
core  

Purchasing equipment [PDF]

open access: yesAnaesthesia, 1991
J, Lumley, D A, Zideman
openaire   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Consumer Purchasing: When Does Corporate Social Responsibility Matter? [PDF]

open access: yes, 2016
Almost all companies engage in corporate social responsibility (CSR) programs, and often times consumers are unaware of this. As societal pressures on companies and organizations to be more responsible increases, so have the practices companies have ...
Blecker, Abigail
core   +1 more source

Do Purchase or Do no Purchase? Customer Purchasing Decisions

open access: yesAdvances in Social Science, Education and Humanities Research, 2021
null Wasiman   +4 more
openaire   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

A COMPARISON OF SUPPLIERS AND THEIR LEVELS WITHIN THE PURCHASING PROCESS [PDF]

open access: yesActa Logistica, 2015
Due to the effects of the global economic crisis, manufacturing companies have been forced to look for savings in all areas. Many manufacturing entities in recent years have not sufficiently optimized their purchasing processes.
Petr Besta   +2 more
doaj  

Revolution through electronic purchasing [PDF]

open access: yes, 1997
Automation is finding its way in the world of purchasing. This development could evoke dramatic effects in the long term, not only on purchasing but even on the market place itself.
Telgen, Jan
core   +4 more sources

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