Results 31 to 40 of about 7,102 (233)

L'ipotensione

Italian Journal of Medicine, 2016
Ipotensione: concetti generali e classificazione A. Lagi Ipotensione acuta G. Costantino, M. Bonzi Ipotensione cronica non neurogena A. Lagi Ipotensione neurogena nella multiple system atrophy e nella pure autonomic failure R. Furlan, F.
A. Lagi, G. Pinna, R. Nardi
doaj   +1 more source

Alpha-synuclein in Parkinson’s disease and other synucleinopathies: from overt neurodegeneration back to early synaptic dysfunction

Cell Death and Disease, 2023
Although the discovery of the critical role of α-synuclein (α-syn) in the pathogenesis of Parkinson’s disease (PD) is now twenty-five years old, it still represents a milestone in PD research.
Paolo Calabresi, Alessandro Mechelli, Giuseppina Natale, Laura Volpicelli-Daley, Giulia Di Lazzaro, Veronica Ghiglieri   +5 more
doaj   +1 more source

Alpha-Synuclein Strain Variability in Body-First and Brain-First Synucleinopathies

Frontiers in Aging Neuroscience, 2022
Pathogenic alpha-synuclein (asyn) aggregates are a defining feature of neurodegenerative synucleinopathies, which include Parkinson's disease, Lewy body dementia, pure autonomic failure and multiple system atrophy.
Mie Kristine Just, Mie Kristine Just, Hjalte Gram, Vasileios Theologidis, Poul Henning Jensen, K. Peter R. Nilsson, Mikael Lindgren, Karoline Knudsen, Karoline Knudsen, Per Borghammer, Per Borghammer, Nathalie Van Den Berge, Nathalie Van Den Berge   +12 more
doaj   +1 more source

Autonomic Dysfunction in α-Synucleinopathies

Frontiers in Neurology, 2019
The α-synucleinopathies are a group of neurodegenerative diseases characterized by abnormal accumulation of insoluble α-synuclein in neurons and glial cells, comprising Parkinson's disease (PD), dementia with Lewy bodies (DLB) and multiple system atrophy
José Javier Mendoza-Velásquez, José Javier Mendoza-Velásquez, Juan Francisco Flores-Vázquez, Juan Francisco Flores-Vázquez, Evalinda Barrón-Velázquez, Ana Luisa Sosa-Ortiz, Ben-Min Woo Illigens, Ben-Min Woo Illigens, Timo Siepmann, Timo Siepmann   +9 more
doaj   +1 more source

Frequent Nocturnal Vocalization in Pure Autonomic Failure [PDF]

Journal of International Medical Research, 2008
Nocturnal vocalization is frequent in Parkinson's disease patients with rapid eye movement (REM) sleep behaviour disorder (RBD). We investigated the frequency of nocturnal vocalization and other sleep problems in patients with pure autonomic failure (PAF) and compared the results with idiopathic Parkinson's disease (IPD) and dementia with Lewy bodies (
K, Kashihara, M, Ohno, S, Kawada, T, Imamura   +3 more
openaire   +2 more sources

Stress induced hypotension in pure autonomic failure [PDF]

Journal of Neurology, Neurosurgery & Psychiatry, 2006
A 47 year old woman with pure autonomic failure complained of dizziness during emotional stress. Emotional stimuli have not previously been reported to cause hypotension in patients with autonomic failure. In the patient, ambulatory blood pressure recording revealed severe hypotension (50/30 mm Hg) after a stressful event.
R D, Thijs, J G, van Dijk
openaire   +2 more sources

Cutaneous Phosphorylated Alpha‐Synuclein in Lewy Body Dementia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the test performance of cutaneous phosphorylated alpha‐synuclein (P‐SYN) in dementia with Lewy bodies (DLB), individuals with reduced Montreal Cognitive Assessment (MoCA) and healthy controls. Methods This is the first subgroup analysis of the Synuclein‐One study, a prospective, blinded study evaluating P‐SYN detection ...
Christopher H. Gibbons, Todd Levine, Charles H. Adler, Bailey Bellaire, Ningshan Wang, Pinky Agarwal, Georgina M. Aldridge, Alexandru Barboi, Daniel Claassen, Virgilio G. H. Evidente, Douglas Galasko, Alejandra Gonzalez‐Duarte, Ramon Gil, Mark Gudesblatt, Stuart H. Isaacson, Horacio Kaufmann, Pravin Khemani, Rajeev Kumar, Guillaume Lamotte, Andy J. Liu, Nikolaus R. McFarland, Mitchell G. Miglis, Adam Reynolds, Gregory A. Sahagian, Marie‐Helene Saint‐Hilaire, Julie B. Schwartzbard, Wolfgang Singer, Michael J. Soileau, Steven Vernino, Patricio Millar Vernetti, Oleg Yerstein, Roy Freeman   +31 more
wiley   +1 more source

Characterization of the symptoms of neurogenic orthostatic hypotension and their impact from a survey of patients and caregivers

BMC Neurology, 2018
Background Neurogenic orthostatic hypotension (nOH) results from impaired vasoconstriction due to dysfunction of the autonomic nervous system and is commonly associated with Parkinson disease (PD), multiple system atrophy (MSA), and pure autonomic ...
Daniel O. Claassen, Charles H. Adler, L. Arthur Hewitt, Christopher Gibbons   +3 more
doaj   +1 more source

Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy

Advanced Functional Materials, EarlyView.
FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao, Yejing Zhu, Hengchao Yu, Jun Zhu, Bo Wang, Yu Qiao, Zhimin Tian, Junlong Zhao, Lei Liu   +8 more
wiley   +1 more source

Pure autonomic failure followed by amyotrophy

Neurology, 2007
Features of autonomic dysfunction may develop late in amyotrophic lateral sclerosis (ALS), but pure autonomic failure with subsequent amyotrophy has not been recognized. We report the rare combination of pure autonomic failure followed by gradually progressive, isolated anterior horn cell disease.
Irani, SR, Mathias, C, Orrell, R
openaire   +2 more sources