Results 101 to 110 of about 41,889 (298)

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Disordered eating in a Swedish community sample of adolescent girls: subgroups, stability, and associations with body esteem, deliberate self-harm and other difficulties

Journal of Eating Disorders, 2018
Background The developmental study of subtypes of disordered eating (DE) during adolescence may be relevant to understand the development of eating disorders.
Njördur Viborg, Margit Wångby-Lundh, Lars-Gunnar Lundh, Ulf Wallin, Per Johnsson   +4 more
doaj   +1 more source

Perancangan Sistem Pengaturan Purging Pada Proton Exchange Membrane Fuel Cell (PEMFC) Tipe Open Cathode Nntuk Meningkatkan Efisiensi [PDF]

, 2023
Pengaturan purging pada Proton Exchange Membrane Fuel Cell (PEMFC) bertujuan untuk menghindari flooding yang disebabkan adanya penumpukan air pada anoda.
Sausa, Awang Ganda
core  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

OPTIMALISASI PURGING MENGGUNAKAN NITROGEN UNTUK FREE GAS TANGKI MUATAN PADA SAAT DRY DOCK DI KAPAL LPG/C GAS NURI ARIZONA [PDF]

, 2021
Secondnandra, Alzira Fitra 531611105900 N, 2021, “Optimalisasi Purging Menggunakan Nitrogen Untuk Free Gas Tangki Muatan Pada Saat Dry Dock Di Kapal LPG/C Gas Nuri Arizona”, Program Diploma IV, Program Studi Nautika, Politeknik Ilmu Pelayaran Semarang,
ALZIRA, FITRA SECONDNANDRA
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

(Ex)purging: Anaïs Nin cleans out the diary [PDF]

, 2014
(Ex)purging: Anaïs Nin Cleans Out the Diary.
Ruth Charnock (17155372)
core   +2 more sources

Purging of surface condenser tubes CA-719: Study report [PDF]

, 1958
This document provides the conclusions and recommendations of the study of purging of surface condenser tubes ...
Wood, V. W.
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source