Results 111 to 120 of about 45,662 (293)

Meaning and Clinical Application of the Method of South-Reducing and North-Reinforcing

针刺研究, 1998
Through studying "Classic on Difficulty· 75th Difficulty", the writer clarifies the means of "the Ensess of East, the Difficent of West, Purging the South and Reinforcing the North".
魏连海, 尚秀葵
doaj   +2 more sources

Childhood trauma and disordered eating behaviors in youth: examining individual types, cumulative numbers, and latent patterns

Child and Adolescent Psychiatry and Mental Health
Background Although traumatic experiences in childhood have been recognized as contributors to disordered eating behaviors, critical gaps remain in our understanding.
Yan’e Lu, Wenwen Xu, Suying Wu, Liangliang Ping, Qingyan Wu, Yuyun Huang, Li Zhang, Farong Liu, Jia Jia Liu, Jianyu Que   +9 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Recirculating Purging System for Hemispherical Net Radiometers [PDF]

, 1977
A purging system was developed to prevent internal condensation in hemispherical net radiometers without frequent changing of desiccant. Continuous recirculation of dry air through the radiometer and a desiccant tube prevented condensate formation during
Stevens, J.L., Wright, J.L.
core  

Purgatives and Laxatives [PDF]

BMJ, 1960
openaire   +3 more sources

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Differential dynamic responses of luteinizing hormone to gonadotropin releasing hormone in patients affected by bulimia nervosa-purging versus non-purging type

, 1997
OBJECTIVE:Aim of the study was to investigate the presence of underlying abnormalities affecting the hypothalamus-pituitary-gonadal axis in 13 normal weight eumenhorreic bulimics as expressed by a different gonadotropin response to gonadotropin releasing
RAMACCIOTTI, CARLA EMILIA, DELL'OSSO, LILIANA, PISTOIA S, PUCCI E., GUIDI L, BONDI E, COLI E   +6 more
core  

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Simulation of PEM Fuel Cell Shutdown Purging Using VOFbased Workflow

Gas purging is a critical operation in low-temperature PEM fuel cells (PEMFC) for removing the accumulated liquid water, preventing freezing after shutdown, and maintaining the cell’s durability. In this work, a high-fidelity workflow based on the Volume-
Janiga, G., Sanchez-Gamero, S., Fink, C., Edelbauer, W., Gavaises, M.   +4 more
core   +1 more source