Results 1 to 10 of about 12,197 (134)

Functional Cargo in Membrane Vesicles From a Citrus Pathogen. [PDF]

Environ Microbiol Rep
ABSTRACT The causative agent of citrus canker disease, Xanthomonas citri pv. citri, was found to produce copious amounts of outer membrane vesicles (OMVs), frequently forming long membranous tubes under different culture conditions. Lipidomic analysis revealed significant differences in lipid composition between purified vesicles in relation to whole ...
Araujo GG, Conforte MM, da Purificação AD, Todeschini I, Llontop EE, Angeli CB, Inague A, Yoshinaga MY, de Souza RF, Papai R, Luz MS, Miyamoto S, Palmisano G, Farah CS, Guzzo CR.   +14 more
europepmc   +2 more sources

Biochemical Characterization of a Kunitz-Type Protease Inhibitor From Mimosa regnellii and Its Effects on Melanoma Cell Viability and Angiogenesis. [PDF]

Chem Biodivers
A Kunitz‐type serine protease inhibitor (JTI) purified from Mimosa regnellii seeds selectively targets melanoma cells. JTI triggers mitochondrial apoptosis, increases ROS and Ca2+ levels, arrests the cell cycle, and suppresses migration and angiogenesis without affecting healthy cells.
Rabêlo LMA, Cardoso PHO, Nobre LTDB, Dos Santos PIM, Lucena SV, Serquiz RP, Bemquerer MP, Rocha HAO, Nader HB, Dos Santos EA, de Oliveira AS, Frihling BEF, Migliolo L.   +12 more
europepmc   +2 more sources

A Novel Kunitz Trypsin Inhibitor from Enterolobium gummiferum Seeds Exhibits Antibiofilm Properties against Pathogenic Yeasts [PDF]

Molecules
Plant peptidase inhibitors play crucial roles in plant defence mechanisms and physiological processes. In this study, we isolated and characterised a Kunitz trypsin inhibitor from Enterolobium gummiferum seeds named EgPI (E.
Matheus M. da Silva, Caio F. R. de Oliveira, Claudiane V. Almeida, Ismaell A. S. Sobrinho, Maria L. R. Macedo   +4 more
doaj   +2 more sources

Structural Insights Into Papain-Derived Synthetic Antibacterial Peptides for Targeting Klebsiella pneumoniae. [PDF]

Chem Biol Drug Des
The synthetic peptides WK‐MAP1 and WG‐MAP2, bioinspired by papain, demonstrated optimized activity, particularly against multidrug‐resistant Klebsiella pneumoniae, with improved sequence interaction profiles, membrane affinity, and predicted antimicrobial and antibiofilm efficacy, supporting their potential as therapeutic peptide candidates.
Ferreira MA, Silva PSE, Lacerda AP, Franco PM, da Silva FFD, de Souza TF, Macedo MLR, Migliolo L, de Oliveira JS.   +8 more
europepmc   +2 more sources

Negative Impact of Dental Wastewater on the Environment and Human Health: A Scoping Review. [PDF]

Water Environ Res
Dental wastewater (DWW) may carry hazardous contaminants (toxic metals, chemicals, and microorganisms) from clinical procedures into municipal sewers and wastewater treatment plants, with potential release to receiving waters. Because treatment may not fully remove all pollutants, the most effective prevention point is source control.
Furini GP, Belarmino RM, Rigo L.
europepmc   +2 more sources

O sono de Epimênides ao meio-dia

Archai: Revista de Estudos sobre as Origens do Pensamento Ocidental, 2023
Mostraremos, a partir da cena das cigarras cantoras do Fedro, as afinidades entre a menção ao perigoso sono ao meio-dia (Phdr. 258e6-259d8) e um episódio mítico da vida de Epimênides.
Rogerio G. de Campos
doaj   +1 more source

Frugivory and seed dispersal in the Cerrado: Network structure and defaunation effects

Biotropica, Volume 55, Issue 4, Page 849-865, July 2023., 2023
We investigated the Cerrado seed dispersal network and the potential impacts of defaunation on it by performing a systematic literature review. The Cerrado network has a heterogeneous structure, slightly nested and considerably modular, and is dominated by generalist species.
Rodrigo Béllo Carvalho, Yadvinder Malhi, Imma Oliveras Menor   +2 more
wiley   +1 more source

Biotechnological production of cyclic dinucleotides—Challenges and opportunities

Biotechnology and Bioengineering, Volume 119, Issue 3, Page 677-684, March 2022., 2022
In this review, recent discoveries and trends in the chemical and biocatalytic synthesis of cyclic dinucleotides (CDNs) are presented. Interest in the synthesis of CDNs, especially cGAMP and cGAMP‐related synthetic CDNs, is high due to their potential for pharmaceutical applications.
Tabea Bartsch, Martin Becker, Jascha Rolf, Katrin Rosenthal, Stephan Lütz   +4 more
wiley   +1 more source

Impact of a large artificial lake on regional climate: A typical meteorological year Meso‐NH simulation results

International Journal of Climatology, Volume 42, Issue 2, Page 1231-1252, February 2022., 2022
Large lakes and artificial reservoirs can affect the meteorological regime of their coastal areas and impact the local climate. This work focuses on the weather impact of the Alqueva reservoir, the largest artificial lake in Western Europe, studied on the basis of mesoscale atmospheric modelling data over the 12‐month period composed in a typical ...
Maksim Iakunin, Edgar F.M. Abreu, Paulo Canhoto, Sara Pereira, Rui Salgado   +4 more
wiley   +1 more source

Aircraft observations and sub‐km modelling of the lake–land breeze circulation over Lake Victoria

Quarterly Journal of the Royal Meteorological Society, Volume 148, Issue 743, Page 557-580, January 2022., 2022
Lake Victoria (pictured) is a hotspot for severe convective storms which pose a great danger to users of the lake. A research aircraft was flown over the lake to sample the lake–land breeze circulation largely responsible for these deadly storms. Lake and land breezes were observed across the eastern shore of the lake in evening and morning flights ...
Beth J. Woodhams, Paul A. Barrett, John H. Marsham, Cathryn E. Birch, Caroline L. Bain, Jennifer K. Fletcher, Andrew J. Hartley, Stuart Webster, Solomon Mangeni   +8 more
wiley   +1 more source