Results 151 to 160 of about 2,131,700 (307)

Purification of phlorotannins from Macrocystis pyrifera using macroporous resins

open access: green, 2017
Allison Leyton   +3 more
openalex   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Social risk profiles and diabetic kidney disease: prevalence and mortality in US adults

open access: yesBMC Public Health
Background Diabetic kidney disease (DKD) is a severe and prevalent complication of diabetes. Social contexts have been increasingly recognized as critical factors in the escalation and ongoing management of chronic diseases, including DKD.
Zishan Lin   +5 more
doaj   +1 more source

Wastewater Purification and All-Solid Z-Scheme Heterojunction ZnO-C/MnO2 Preparation: Properties and Mechanism [PDF]

open access: gold, 2022
Lei Zhao   +9 more
openalex   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Predicting anemia management in dialysis patients using open-source machine learning libraries

open access: yesRenal Replacement Therapy
Background Managing anemia in patients with end-stage kidney disease (ESKD) undergoing hemodialysis (HD) is a major clinical challenge. It requires precise hemoglobin (Hb) control while minimizing erythropoiesis-stimulating agent (ESA) dosages to reduce ...
Takahiro Inoue   +3 more
doaj   +1 more source

Culture purification and DNA extraction procedures suitable for next-generation sequencing of euglenids [PDF]

open access: hybrid, 2018
Natalia Gumińska   +5 more
openalex   +1 more source

Home - About - Disclaimer - Privacy