Results 41 to 50 of about 1,326,906 (303)

PURIFICATION OF MERCURY. [PDF]

Journal of the American Chemical Society, 1909
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openaire   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Review of clinical characteristics and mortality outcomes in patients on maintenance hemodialysis during the Omicron surge: a single center experience

BMC Public Health
Background This hemodialysis center experienced the pandemic from December 2022 to January 2023. Therefore, we sought to describe the clinical characteristics and mortality outcomes in hemodialysis patients during this Omicron surge. Methods According to
Yiyang Xue, Weiwei Feng, Ling Shi, Ning Cui, Wei Zhang, Junxiu Dong, Chunying Li, Jinjin Hu, Junjun Wei   +8 more
doaj   +1 more source

Circ_0114428 promotes proliferation, fibrosis and EMT process of high glucose-induced glomerular mesangial cells through regulating the miR-185-5p/SMAD3 axis

Autoimmunity, 2022
Circular RNA (circRNA) has been confirmed to be the key regulators of diabetic nephropathy (DN) progression. However, the role of circ_0114428 in the DN progression remains unclear. Glomerular mesangial cells (GMCs) were treated with high glucose (HG) to
Bo Li, Guijiang Sun, Haibo Yu, Jia Meng, Fang Wei   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Facilitators and barriers to self-management among patients with maintenance hemodialysis in central China: a qualitative study

BMC Nephrology
Objective This study aimed to explore the facilitative and obstructive factors of self-management in patients undergoing maintenance hemodialysis to provide a reference for improving patient self-management in China.
Lin Zhang, Yuping Li, Xin Meng, Mengfan He, Yongzhen Guo, Hongtao Zhang   +5 more
doaj   +1 more source

Hepatitis C virus and carpal tunnel syndrome in hemodialysis patients: a single center cross-sectional study

Renal Failure, 2020
Objectives Carpal tunnel syndrome (CTS) is a common complication in maintenance hemodialysis (MHD) patients and leads to disabilities and increased risk of mortality. Hepatitis C virus (HCV) infection is associated with inflammatory and oxidative stress,
Ling Yu, Shen Shen, Yuan Zu, Jia Huang, Han Li, Shixiang Wang   +5 more
doaj   +1 more source

Serpin E1 mediates the induction of renal tubular degeneration and premature senescence upon diabetic insult

Scientific Reports, 2023
As a leading cause of chronic kidney disease, diabetic kidney disease (DKD) involves insidious but progressive impairments of renal tubules, and is associated with premature renal aging. The underlying pathomechanisms remain elusive. Post hoc analyses of
Bo Han Chen, Xiao Qing Lu, Xian Hui Liang, Pei Wang   +3 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source