Genome-Wide Analysis Unveils the Evolutionary Impact of Allopolyploidization on the 14-3-3 Gene Family in Rapeseed (<i>Brassica napus</i> L.). [PDF]
Duan S, Wang J.
europepmc +1 more source
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
How to Handle Hard-to-Purify Polymers: Ammonium Sulfate Precipitation of rPEG as a Prototype for Amorphous and Flexible Polymers. [PDF]
Simon L, Dreier P, Frey H.
europepmc +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Step-by-Step Real-Time Electron Paramagnetic Resonance Monitored Protocol for Synthesizing a Nitroxide-Functionalized Periodic Mesoporous Organosilica. [PDF]
Morais T +6 more
europepmc +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Ritual to defeat infernal deities and to purify a house, tablet concordance KBo X 45 - CTH 446
Notes on the ritual performed to defeat infernal deities and to purify a house based on the tablet concordance KBo X 45 (inventory no. 244/p). Emmanuel Laroche translated this text as "Rituel aux divinités infernales : purification d'une maison,” and ...
Gonnet-Bağana, Hatice
core
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Retraction: Ph-triazole as a therapeutic agent for pancreatic cancer: Synthesis, in silico, and in vitro evaluation. [PDF]
PLOS One Editors.
europepmc +1 more source
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler +3 more
wiley +1 more source

