Results 81 to 90 of about 146,626 (295)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Arabidopsis thaliana homologs of SWR1-C subunits co-purify with N-TAP ARP6 and C-TAP ARP6.
, 2019 Arabidopsis thaliana homologs of SWR1-C subunits co-purify with N-TAP ARP6 and C-TAP ARP6.
Dylan H. Holder (7135052) +3 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Solid Phase Extraction Purification of Saliva Samples for Antipsychotic Drug Quantitation
Molecules, 2018 Saliva is far less popular as a diagnostic material than blood. This has resulted in a lack of procedures for the sampling and handling of saliva, e.g., effective ways to purify endogenous compounds from saliva to enable a simultaneous determination of ...
Ewelina Dziurkowska, Marek Wesolowski
doaj +1 more source
Detect, purify and identify an Urotensin II metabolizing enzyme
, 2010 Das Ziel dieser Arbeit war, ein Urotensin II (UII) metabolisierendes Enzym (UME) aus dem Gewebe von Schweinenieren aufzuspüren, zu reinigen und zu identifizieren.
Ahmed, Shenge
core +1 more source
Proteomic analysis of protein purified derivative of Mycobacterium bovis
Journal of Translational Medicine, 2017 Background Tuberculin skin test based on in vivo intradermal inoculation of purified protein derivative from Mycobacterium bovis (bPPD) is the diagnostic test for the control and surveillance of bovine tuberculosis (bTB).
Sante Roperto +8 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
, 2012 The invention provides a method to purify a recombinant virus protein from microbial cells. Hydrophobic interaction Chromatography (HIC) is used to capture recombinant virus protein from both clarified and unclarified microbial cell ...
Tey, Beng Ti +2 more
core +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Memory Leaks Detection in Java by Bi-Abductive Inference [PDF]
, 2013 Distefano, Dino, Filipović, Ivana
core +4 more sources