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SAICAR Drives T Regulatory Cell Differentiation and FOXP3 Maintenance to Promote Immunotherapy Resistance. [PDF]

Cancer Res
Li M, Chen Y, Liu A, Wu Q, Huang C, Song D, Hu F, Lan J, Huang C, Hu J, Wang G.   +10 more
europepmc   +1 more source

SIRT6-GLUL axis: rewiring nitrogen metabolism in intrahepatic cholangiocarcinoma. [PDF]

Gut
Zhou H, Li H, Wu N, Calvisi DF.
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Transcriptome sequencing combined with experimental verification to explore potential key genes related to uric acid in diabetic retinopathy. [PDF]

PLoS One
Liang H, Yang T, Lu F, Lin L, Liang H.
europepmc   +1 more source

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Analysis of Purine in Purine-Rich Cauliflower

Nucleosides, Nucleotides and Nucleic Acids, 2010
Purine is a general term for purine nucleotides, nucleosides, bases, and nucleic acid. The amount of purine nucleotides, nucleosides, and bases in purine-rich cauliflower was determined with the use of LC-MS and HPLC, and the ratio of these molecules were compared with in raw and in heated condition.
N Yamaoka, Kazuma Mawatari
exaly   +3 more sources

The biosynthesis of the purines

Ergebnisse der Physiologie Biologischen Chemie und Experimentellen Pharmakologie, 1959
Of the many problems which confront the biologist in his understanding of the operations of the cell, the synthesis of biologically important substances is now the most amenable to solution. It has been the domain of the biochemist to probe into the integrated cellular system by dissembling its enzymatic machinery as a means of studying the complex ...
S C, HARTMAN, J M, BUCHANAN
openaire   +2 more sources

PURINE PHOTOPRODUCTS*

Photochemistry and Photobiology, 1988
Abstract— DNA purine modifications by ultraviolet irradiation have not been as extensively studied as those of pyrimidines. However, a number of such reactions have been identified. These include photochemical addition of amino acids, photoalkylation by alcohols, amines and other compounds, photochemical activation of procarcinogens to mutagenic ...
N J, Duker, P E, Gallagher
openaire   +2 more sources

Feedback Control of Purine Biosynthesis by Purine Ribonucleotides

Nature, 1959
IN recent years a number of biosynthetic sequences have been shown to be regulated by feedback mechanisms, which have been of two general types, the first involving regulation of the activity of an enzyme by an inhibitory effect of an end-product1,2, the second involving regulation of the rate of synthesis of an enzyme by negative-induction, or ...
J B, WYNGAARDEN, D M, ASHTON
openaire   +2 more sources

Abnormal Purine Metabolism and Purine Overproduction in a Patient Deficient in Purine Nucleoside Phosphorylase

New England Journal of Medicine, 1976
To delineate the normal function of purine nucleoside phosphorylase and to understand the pathogenesis of the immune dysfunction associated with deficiency of this enzyme, we studied purine metabolism in a patient deficient in purine nucleoside phosphorylase, her erythrocytes and cultured fibroblasts.
A, Cohen, D, Doyle, D W, Martin, A J, Ammann   +3 more
openaire   +2 more sources