Results 301 to 310 of about 187,335 (337)
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On the relevance of hydroxyl radical to purine DNA damage
Free radical research, 2021Hydroxyl radical (HO•) is the most reactive toward DNA among the reactive oxygen species (ROS) generated in aerobic organisms by cellular metabolisms. HO• is generated also by exogenous sources such as ionizing radiations.
C. Chatgilialoglu +4 more
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Analysis of Purine in Purine-Rich Cauliflower
Nucleosides, Nucleotides and Nucleic Acids, 2010Purine is a general term for purine nucleotides, nucleosides, bases, and nucleic acid. The amount of purine nucleotides, nucleosides, and bases in purine-rich cauliflower was determined with the use of LC-MS and HPLC, and the ratio of these molecules were compared with in raw and in heated condition.
M Aoki +8 more
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Purine Release, Metabolism, and Signaling in the Inflammatory Response.
Annual Review of Immunology, 2019ATP, NAD+, and nucleic acids are abundant purines that, in addition to having critical intracellular functions, have evolved extracellular roles as danger signals released in response to cell lysis, apoptosis, degranulation, or membrane pore formation ...
J. Linden, F. Koch-Nolte, G. Dahl
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Feedback Control of Purine Biosynthesis by Purine Ribonucleotides [PDF]
Nature, 1959 IN recent years a number of biosynthetic sequences have been shown to be regulated by feedback mechanisms, which have been of two general types, the first involving regulation of the activity of an enzyme by an inhibitory effect of an end-product1,2, the second involving regulation of the rate of synthesis of an enzyme by negative-induction, or ...
James B. Wyngaarden, Doris M. Ashton
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3 Purine, Purine Nucleoside, and Purine Nucleotide Aminohydrolases
1971Publisher Summary This chapter discusses the chemical significance of adenosine aminohydrolase, 5′-adenylic acid aminohydrolase, adenine nucleoside, nucleotide aminohydrolase, guanine aminohydrolase, and guanosine aminohydrolase. The partially purified adenine aminohydrolase from Azotobacter vinelandii catalyzes the anaerobic conversion of adenine ...
C.H. Suelter, C.L. Zielke
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Protonation-deprotonation of purines and purine nucleosides
Journal of Molecular Structure: THEOCHEM, 1989Abstract The protonation of purines and purine nucleosides at N7 and the HC8 acidity of the cations have been explored by semi-empirical and ab initio MO ...
Donald W. Boerth, Pradip K. Bhowmik
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Biochemical Society Transactions, 1981
Abstract The inherited disorders of purine metabolism associated with renal disease are listed in Table 24.1. They are the sole cause of only a small proportion of all renal disease and are therefore best considered as part of the overall problem of purine, especially uric acid metabolism-related renal disease.
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Abstract The inherited disorders of purine metabolism associated with renal disease are listed in Table 24.1. They are the sole cause of only a small proportion of all renal disease and are therefore best considered as part of the overall problem of purine, especially uric acid metabolism-related renal disease.
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Photochemistry and Photobiology, 1988
Abstract— DNA purine modifications by ultraviolet irradiation have not been as extensively studied as those of pyrimidines. However, a number of such reactions have been identified. These include photochemical addition of amino acids, photoalkylation by alcohols, amines and other compounds, photochemical activation of procarcinogens to mutagenic ...
N J, Duker, P E, Gallagher
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Abstract— DNA purine modifications by ultraviolet irradiation have not been as extensively studied as those of pyrimidines. However, a number of such reactions have been identified. These include photochemical addition of amino acids, photoalkylation by alcohols, amines and other compounds, photochemical activation of procarcinogens to mutagenic ...
N J, Duker, P E, Gallagher
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New England Journal of Medicine, 1976
To delineate the normal function of purine nucleoside phosphorylase and to understand the pathogenesis of the immune dysfunction associated with deficiency of this enzyme, we studied purine metabolism in a patient deficient in purine nucleoside phosphorylase, her erythrocytes and cultured fibroblasts.
David W. Martin +3 more
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To delineate the normal function of purine nucleoside phosphorylase and to understand the pathogenesis of the immune dysfunction associated with deficiency of this enzyme, we studied purine metabolism in a patient deficient in purine nucleoside phosphorylase, her erythrocytes and cultured fibroblasts.
David W. Martin +3 more
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New England Journal of Medicine, 1970
"The biochemistry of uric acid and its relation to gout" was recently (1963) reviewed in a series of articles that appeared in the Medical Progress section of the Journal.1 In this series the bioch...
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"The biochemistry of uric acid and its relation to gout" was recently (1963) reviewed in a series of articles that appeared in the Medical Progress section of the Journal.1 In this series the bioch...
openaire +3 more sources