Results 301 to 310 of about 124,162 (316)
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Life Sciences, 1987
The fact that purine nucleotides and nucleosides are so important in normal cellular functions makes their analysis complicated. In order to measure tissue levels, samples have to be very rapidly fixed. Measurement in blood is complicated by the risk of releasing purine nucleotides during the sampling procedure and by the possibility of very rapid ...
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The fact that purine nucleotides and nucleosides are so important in normal cellular functions makes their analysis complicated. In order to measure tissue levels, samples have to be very rapidly fixed. Measurement in blood is complicated by the risk of releasing purine nucleotides during the sampling procedure and by the possibility of very rapid ...
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Theoretical studies on the purine radical induced purine–purine type intrastrand cross-links
Organic & Biomolecular Chemistry, 2019Purine-type radicals can attack their 3′/5′ flanking purine deoxynucleosides forming the purine–purine type DNA intrastrand cross-links.
Shoushan Wang +6 more
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1987
Nucleic acids are comprised of nitrogenous bases (purines and pyrimidines), pentose sugars (ribose and deoxyribose) and phosphate groups. Specific sequences of purines and pyrimidines encode the genetic information of cells and organisms.
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Nucleic acids are comprised of nitrogenous bases (purines and pyrimidines), pentose sugars (ribose and deoxyribose) and phosphate groups. Specific sequences of purines and pyrimidines encode the genetic information of cells and organisms.
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Inhibition of Lipid Peroxidation by Purines and Analogues of Purine
1995The importance of oxygen radicals in tissue injury is widely recognized(1). Mutation, cancer, inflammation, and ageing are thought to be caused by oxygen radicals. It has also been confirmed that lipids are peroxidized by oxygen radicals leading to the damaging effects on cellular constituents. Mickel & Horbar(2) reported that peroxidized lipids affect
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Induction of erythroid differentiation in vitro by purines and purine analogues
Cell, 1976The effectiveness of purines and purine analogues as inducers of erythroid differentiation in cultured murine erythroleukemia cells has been investigated. These cell lines have previously been shown to differentiate in vitro in response to dimethylsulfoxide (DMSO) and a number of other polar solvents.
James F. Gusella, David E. Housman
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1991
Publisher Summary This chapter discusses the important novel basic chemistry of the purine system, and interesting new compounds obtained by established methods. The basic chemistry of the purine system is established for a very long time. Many new procedures for the synthesis of purine derivatives and many thousands of novel nucleoside analogues have
G. Mackenzie, D.F. Ewing
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Publisher Summary This chapter discusses the important novel basic chemistry of the purine system, and interesting new compounds obtained by established methods. The basic chemistry of the purine system is established for a very long time. Many new procedures for the synthesis of purine derivatives and many thousands of novel nucleoside analogues have
G. Mackenzie, D.F. Ewing
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1988
Publisher Summary Purine alkaloids are widely distributed within the plant kingdom. However, their occurrence is limited to dicotyledonous species, preferentially in tropical and subtropical climates. Caffeine and theobromine, methylated derivatives of xanthine, are generally the main purine alkaloids and are regularly accompanied in low ...
Thomas W. Baumann, Peter M. Frischknecht
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Publisher Summary Purine alkaloids are widely distributed within the plant kingdom. However, their occurrence is limited to dicotyledonous species, preferentially in tropical and subtropical climates. Caffeine and theobromine, methylated derivatives of xanthine, are generally the main purine alkaloids and are regularly accompanied in low ...
Thomas W. Baumann, Peter M. Frischknecht
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Purin- und Pyrimidinstoffwechsel [PDF]
, 1973 Purine und Pyrimidine sind die wesentlichen Bestandteile der Nucleinsaure und der Coenzyme. Als solche kommen sie in allen Zellen und somit in der Nahrung vor. Dennoch besteht auch eine intensive Synthese de novo. Krankheiten des Purin- und Pyrimidinstoff-wechsels kommen als vererbliche Stoffwechselkrankheiten unterschiedlicher Pathogenese vor.
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Purines and purine nucleoside analogues as antitumour agents
1990Purines, purine nucleosides and their analogues have been extremely useful as anticancer agents. Robins1, in 1964, reviewed the antitumour activity of purines and purine nucleosides from a structure-activity standpoint. Subsequently, several reviews on this subject have been published2–7.
G. D. Kini, R. K. Robins
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