Results 281 to 290 of about 245,344 (350)

Dapagliflozin Alters Plasma Metabolome in Patients With Type 1 Diabetes During Ketosis

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Use of sodium‐glucose cotransporter 2 inhibitors (SGLT2i) in patients with type 1 diabetes (T1D) is limited by increased risk of ketoacidosis. We aimed to determine metabolic pathways affected by SGLT2i treatment in adults with T1D during ketosis induced by insulin withdrawal.
Rosa Yang, Kevin Cho, Max C. Petersen, Kai E. Jones, Gary J. Patti, Janet B. McGill, Samantha A. DiGruccio   +6 more
wiley   +1 more source

Purine Metabolism Alterations in Patients with Chronic Heart Failure: A Cross-Sectional Study of Associations with Iron Status, Oxidative Stress, and Anemia. [PDF]

Metabolites
Konysbek Y, Turar A, Molotov-Luchanskiy VB, Ponamareva OA.   +3 more
europepmc   +1 more source

Treatment Patterns, Outcomes and Survival Trends in T‐Cell Prolymphocytic Leukemia: A Nationwide Population‐Based Study in the Netherlands

European Journal of Haematology, EarlyView.
ABSTRACT Background T‐cell prolymphocytic leukemia (T‐PLL) is a rare, aggressive mature T‐cell malignancy with limited therapeutic options. Alemtuzumab remains the backbone of therapy, and fit responders are consolidated with allogeneic stem cell transplantation (alloSCT). However, contemporary population‐level outcomes remain poorly defined.
Mirian Brink, Arie C. van der Spek, Jeanette K. Doorduijn, Koen de Heer, Sabina Kersting, Lidwine W. Tick, Doreen G. te Raa, Hanneke M. van der Straaten, Gerrit Jan Veldhuis, Laurens Laterveer, Rogier Mous, Mark‐David Levin, Kees Meijer, Andre Mulder, M. Nijland, Gerwin Huls, Arnon P. Kater, Mar Bellido   +17 more
wiley   +1 more source

Metabolite glues as a means of purine sensing and chemotherapeutic response. [PDF]

Nature
Witus SR, Kober MM, Roh H, Yang Z, Choueiry F, Ghate AS, Titov DV, Rapé M.   +7 more
europepmc   +1 more source

Genetic variants in purine metabolism and treatment resistance in schizophrenia: evidence supporting the adenosine hypothesis - a pilot study. [PDF]

Front Pharmacol
Pjevac M, Blagus T, Oblak A, Vogrinc D, Terzić T, Bon J, Dolžan V.   +6 more
europepmc   +1 more source

Association of serum biomarkers of dietary purine intake with glycaemic control and risk of preterm birth: two prospective cohort studies among pregnant women. [PDF]

EBioMedicine
Hu S, Miao Z, Dong Y, Lai Y, Zhang K, Xiao C, Chen J, Gou W, Fu Y, Wang T, Li F, Shi MQ, Lu S, Wang XH, Yuan J, Wu J, Pan A, Hu W, Shi H, Pan XF, Zheng JS.   +20 more
europepmc   +1 more source

Integrated Transcriptomic and Metabolomic Analyses Reveal Acyl-CoA Dehydrogenase-Mediated Primordium Formation and Metabolite Synthesis in <i>Cordyceps militaris</i>. [PDF]

J Fungi (Basel)
Zhou X, Xue L, Luo Y, Tong X, Guo J.
europepmc   +1 more source

Gas Phase Studies of Purine Base Analogs: Intrinsic Properties and Hypoxanthine-Guanine-(Xanthine) Phosphoribosyltransferase (HG(X)PRT). [PDF]

J Org Chem
Ding X, Zhang L, Kiruba GSM, Lee JK.
europepmc   +1 more source