Results 281 to 290 of about 304,542 (327)
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New insights into purine metabolism in metabolic diseases: role of xanthine oxidoreductase activity.
American Journal of Physiology. Endocrinology and Metabolism, 2020Xanthine oxidoreductase (XOR) consists of two different forms, xanthine dehydrogenase (XDH) and xanthine oxidase (XO), and is a rate-limiting enzyme of uric acid production from hypoxanthine and xanthine. Uric acid is the end-product of purine metabolism
M. Furuhashi
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Disorders of purine biosynthesis metabolism.
Molecular Genetics and Metabolism, 2021Purines are essential molecules that are components of vital biomolecules, such as nucleic acids, coenzymes, signaling molecules, as well as energy transfer molecules.
J. Dewulf, S. Marie, M. Nassogne
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On the relevance of hydroxyl radical to purine DNA damage
Free radical research, 2021Hydroxyl radical (HO•) is the most reactive toward DNA among the reactive oxygen species (ROS) generated in aerobic organisms by cellular metabolisms. HO• is generated also by exogenous sources such as ionizing radiations.
C. Chatgilialoglu +4 more
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Photochemistry and Photobiology, 1988
Abstract— DNA purine modifications by ultraviolet irradiation have not been as extensively studied as those of pyrimidines. However, a number of such reactions have been identified. These include photochemical addition of amino acids, photoalkylation by alcohols, amines and other compounds, photochemical activation of procarcinogens to mutagenic ...
N J, Duker, P E, Gallagher
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Abstract— DNA purine modifications by ultraviolet irradiation have not been as extensively studied as those of pyrimidines. However, a number of such reactions have been identified. These include photochemical addition of amino acids, photoalkylation by alcohols, amines and other compounds, photochemical activation of procarcinogens to mutagenic ...
N J, Duker, P E, Gallagher
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Purine Release, Metabolism, and Signaling in the Inflammatory Response.
Annual Review of Immunology, 2019ATP, NAD+, and nucleic acids are abundant purines that, in addition to having critical intracellular functions, have evolved extracellular roles as danger signals released in response to cell lysis, apoptosis, degranulation, or membrane pore formation ...
J. Linden, F. Koch-Nolte, G. Dahl
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Analysis of Purine in Purine-Rich Cauliflower
Nucleosides, Nucleotides and Nucleic Acids, 2010Purine is a general term for purine nucleotides, nucleosides, bases, and nucleic acid. The amount of purine nucleotides, nucleosides, and bases in purine-rich cauliflower was determined with the use of LC-MS and HPLC, and the ratio of these molecules were compared with in raw and in heated condition.
N, Yamaoka +8 more
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De novo and salvage purine synthesis pathways across tissues and tumors.
CellPurine nucleotides are vital for RNA and DNA synthesis, signaling, metabolism, and energy homeostasis. To synthesize purines, cells use two principal routes: the de novo and salvage pathways.
Diem H. Tran +24 more
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Biochemical Society Transactions, 1981
Abstract The inherited disorders of purine metabolism associated with renal disease are listed in Table 24.1. They are the sole cause of only a small proportion of all renal disease and are therefore best considered as part of the overall problem of purine, especially uric acid metabolism-related renal disease.
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Abstract The inherited disorders of purine metabolism associated with renal disease are listed in Table 24.1. They are the sole cause of only a small proportion of all renal disease and are therefore best considered as part of the overall problem of purine, especially uric acid metabolism-related renal disease.
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ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
F. Seela, N. Ramzaeva, H. Rosemeyer
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AbstractFor Abstract see ChemInform Abstract in Full Text.
F. Seela, N. Ramzaeva, H. Rosemeyer
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3 Purine, Purine Nucleoside, and Purine Nucleotide Aminohydrolases
1971Publisher Summary This chapter discusses the chemical significance of adenosine aminohydrolase, 5′-adenylic acid aminohydrolase, adenine nucleoside, nucleotide aminohydrolase, guanine aminohydrolase, and guanosine aminohydrolase. The partially purified adenine aminohydrolase from Azotobacter vinelandii catalyzes the anaerobic conversion of adenine ...
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