Results 321 to 329 of about 311,690 (329)

New insights into purine metabolism in metabolic diseases: role of xanthine oxidoreductase activity.

American Journal of Physiology. Endocrinology and Metabolism, 2020
Xanthine oxidoreductase (XOR) consists of two different forms, xanthine dehydrogenase (XDH) and xanthine oxidase (XO), and is a rate-limiting enzyme of uric acid production from hypoxanthine and xanthine. Uric acid is the end-product of purine metabolism
M. Furuhashi
semanticscholar   +1 more source

Purine Release, Metabolism, and Signaling in the Inflammatory Response.

Annual Review of Immunology, 2019
ATP, NAD+, and nucleic acids are abundant purines that, in addition to having critical intracellular functions, have evolved extracellular roles as danger signals released in response to cell lysis, apoptosis, degranulation, or membrane pore formation ...
J. Linden, F. Koch-Nolte, G. Dahl
semanticscholar   +1 more source

Disorders of purine biosynthesis metabolism.

Molecular Genetics and Metabolism, 2021
J. Dewulf, S. Marie, M. Nassogne
semanticscholar   +1 more source

Targeting purine synthesis in ASS1-expressing tumors enhances the response to immune checkpoint inhibitors

Nature Cancer, 2020
R. Keshet, R. Keshet, J. Lee, J. Lee, Lital N Adler, Muhammed Iraqi, Y. Ariav, L. Lim, Shaul Lerner, S. Rabinovich, R. Oren, Rotem Katzir, Hila Tishler, Noa Stettner, Omer Goldman, Hadas Landesman, Sivan Galai, Y. Kuperman, Yuri Kuznetsov, A. Brandis, Tevie Mehlman, S. Malitsky, M. Itkin, S. E. Koehler, Yongmei Zhao, Keyur Talsania, Tsai-wei Shen, N. Peled, I. Ulitsky, A. Porgador, E. Ruppin, A. Erez   +31 more
semanticscholar   +1 more source

A high-yielding, strictly regioselective prebiotic purine nucleoside formation pathway

Science, 2016
S. Becker, Ines Thoma, Amrei Deutsch, T. Gehrke, P. Mayer, H. Zipse, T. Carell   +6 more
semanticscholar   +1 more source

Purine salvage in plants.

Phytochemistry, 2018
H. Ashihara, C. Stasolla, T. Fujimura, A. Crozier   +3 more
semanticscholar   +1 more source

meta-C-H Bromination on Purine Bases by Heterogeneous Ruthenium Catalysis.

Angewandte Chemie, 2017
Svenja Warratz, David J. Burns, Cuiju Zhu, Korkit Korvorapun, T. Rogge, J. Scholz, C. Jooss, D. Gelman, L. Ackermann   +8 more
semanticscholar   +1 more source

Evaluation of purine utilization by Lactobacillus gasseri strains with potential to decrease the absorption of food-derived purines in the human intestine

Nucleosides, Nucleotides & Nucleic Acids, 2016
N. Yamada, C. Iwamoto, H. Kano, N. Yamaoka, T. Fukuuchi, K. Kaneko, Y. Asami   +6 more
semanticscholar   +1 more source

Mitochondrial purine and pyrimidine metabolism and beyond

Nucleosides, Nucleotides & Nucleic Acids, 2016
Liya Wang
semanticscholar   +1 more source