Results 81 to 90 of about 1,617,490 (298)

Hydrogen-Bonding Interactions of 8-Substituted Purine Derivatives. [PDF]

ACS Omega, 2023
Osifová Z, Šála M, Dračínský M.
europepmc   +1 more source

Computer-aided rational design of acyclovir analogs to inhibit purine nucleoside phosphorylase

Pharmaceutical and Biomedical Research, 2019
Purine nucleoside phosphorylase (PNP) is one of the major enzymes in the purine salvage pathway. It is responsible for the elevation of deoxyguanosine, and thus considered as the potent target in T-cell lymphoma.
Nusrat Jahan Selsi, Lira Barua, Debpriya Bhattacharjee, Gulamur Rahman, Syeda Sakiatuz Zannat, Najia Absar Munia, Rubaiyat Fahad, Tanjiba Harun Bipasha, Azizur Rahman, Raju Dash   +9 more
doaj  

Synthesis of 9-Cinnamyl-9H-purine Derivatives as Novel TLR4/MyD88/NF-κB Pathway Inhibitors for Anti-inflammatory Effects. [PDF]

ACS Med Chem Lett, 2023
Pham L, Jiang R, Liu Z, Nguyen M, Nguyen Y, Gong Y, Bi Y, Kim HR, Kim YR, Kim G.   +9 more
europepmc   +1 more source

Newly Synthesized Anticancer Purine Derivatives Inhibiting p-EIF4E Using Surface-Modified Lipid Nanovesicles. [PDF]

ACS Omega, 2023
Attia RT, Ewida MA, Khaled E, Fahmy SA, Fawzy IM.   +4 more
europepmc   +1 more source

The Excretion of Purine Derivatives in Dogs [PDF]

Biochemical Journal, 1925
E, Langfeldt, J, Holmsen
openaire   +2 more sources

A Universal Nucleoside‐to‐Nucleoside‐5′‐Triphosphate Enzyme Cascade Driven by Polyphosphate

Angewandte Chemie International Edition, EarlyView.
Nucleoside‐5′‐triphosphates (NTPs) are essential components for the generation of nucleic acids, yet their chemical synthesis is hindered by the low yield of nucleoside phosphorylation. Here, we present a universal, two‐enzyme nucleoside‐to‐NTP cascade that is driven by polyphosphate.
Jonathan P. Suess, Nicolas V. Cornelissen   +1 more
wiley   +1 more source

Synthesis of Novel 2,9-Disubstituted-6-morpholino Purine Derivatives Assisted by Virtual Screening and Modelling of Class I PI3K Isoforms. [PDF]

Polymers (Basel), 2023
Lobo V, Rocha A, Castro TG, Carvalho MA.
europepmc   +1 more source

Evaluation of the Sublimation Process of Some Purine Derivatives: Sublimation Rate, Activation Energy, Mass Transfer Coefficients and Phenomenological Models. [PDF]

Materials (Basel), 2022
Cleminte CI, Ionita D, Lisa C, Cristea M, Mamaligă I, Lisa G.   +5 more
europepmc   +1 more source

Effect of Cyclic Heat Exposure on the Growth Performance and Metabolism of Broilers Fed Palm Kernel Meal

Animal Research and One Health, EarlyView.
The aim of our study is to evaluate the interaction between HS and the incorporation of PKM in broiler chicken diets, as well as its effect on growth performance and metabolism. Based on the results obtained, PKM supplementation failed to mitigate the adverse effects of heat stress in broiler chickens. ABSTRACT The aim of this study was to evaluate the
Ahmed Mijiyawa, Elham Ghashghaei, Okasha Hamada, Huimin Wang, Lijing Sun, Yendouhamtchié Nadiedjoa, Dan Wang, Zhengkai Yue, Clarice Maa Maa Temhoul, Maxwell Ansong Okai, Muhammad Faisal Riaz, Felix Kwame Amevor, Wéré Pitala, Hai Lin   +13 more
wiley   +1 more source

Creatinine as a Urinary Marker of the Purine Derivatives Excretion in Urine Spot Samples of Lambs Fed Peach Palm Meal. [PDF]

Animals (Basel), 2022
Pereira TCJ, Pereira MLA, Carvalho GGP, Silva HGO, Dos Santos AB, Pina DDS, Sousa LB.   +6 more
europepmc   +1 more source