Results 281 to 290 of about 1,394,357 (370)

Yeast Culture Supplementation Improves Meat Quality by Enhancing Immune Response and Purine Metabolism of Small-Tail Han Sheep (<i>Ovis aries</i>). [PDF]

Int J Mol Sci
Bai X, Wang L, Sun H, Sun L, An J, Fu S, Zhao M, Liu F, Ren X, Liu Z, He J, Liu Y.   +11 more
europepmc   +1 more source

Estrogen-mediated inhibition of purine metabolism and cell cycle arrest as a novel therapeutic approach in colorectal cancer

Batoul Abi Zamer, Jasmin Shafarin, Basma M. Sharaf, HamzaM Al Hroub, Nelson C. Soares, Mohammad H. Semreen, Mawieh Hamad, Jibran Sualeh Muhammad   +7 more
openalex   +1 more source

Narrative review of severe combined immunodeficiency—a purine metabolism disorder

, 2018
Jasmine Alsukhon, Ahmed Elisa, Shibani Kanungo, Roua Azmeh   +3 more
openalex   +1 more source

Biocatalytic Construction of a Chemical Exchange Saturation Transfer Magnetic Resonance Imaging Nucleoside Probe: Synthesis and Evaluation of 5‐Methyl‐5,6‐Dihydrothymidine

Advanced Synthesis &Catalysis, Volume 368, Issue 1, January 2026.
Al‐Hilfi et al. present a biocatalytic strategy for synthesizing 5‐methyl‐5,6‐dihydrothymidine (5‐MDHT), a sensitive MRI contrast agent. The study demonstrates that recombinant enzyme catalysis offers an efficient, sustainable, and eco‐friendly alternative to traditional chemical synthesis for producing clinically relevant imaging probes.
Aimen Al‐Hilfi, E. Alejandro Castellanos Franco, Connor J. Grady, Zinia Mohanta, Michael T. McMahon, Milana Bazayeva, Zhen Li, Kenneth M. Merz Jr., Assaf A. Gilad   +8 more
wiley   +1 more source

Microfabricated Neural Biosensors for Detection of Neurotransmitters, Biomarkers, and Small Molecules: Emerging Trends on Self‐Sustained Systems and Energy Harvesting

Advanced Sensor Research, Volume 5, Issue 1, January 2026.
This paper reviews the state of the art and recent developments in thin‐film biosensors for the detection of neurotransmitters, small molecules, and biomarkers within flexible, implantable bioelectronic systems. It covers the main sensing modalities, including electrochemical, plasmonic, acoustic, and magnetic, alongside their materials, transduction ...
Massimo Mariello
wiley   +1 more source

Patchoulene epoxide mitigates colitis and hepatic damage induced by dextran sulfate sodium by regulating the colonic microbiota and purine metabolism. [PDF]

Front Immunol
Chen L, Xie L, Wang L, Zhan X, Zhuo Z, Jiang S, Miao L, Zhang X, Zheng W, Liu TM, He J, Liu Y.   +11 more
europepmc   +1 more source

Adenylosuccinate Synthase 1 Deficiency Improves Energy Metabolism by Promoting Adipose Tissue Re‐esterification via Glycerol Kinase Upregulation

Advanced Science, Volume 13, Issue 1, 5 January 2026.
Working model of Adss1‐mediated regulation of energy metabolism in adipose tissue. In beige adipocytes, Adss1 interacts with HDAC3 in the cytoplasm, and its loss reduces nuclear HDAC3 while increasing cytosolic fractions. This redistribution suppresses HDAC activity and enhances H3K27 acetylation at the Gk promoter, leading to transcriptional ...
Jingjing Sun, Miriayi Alimujiang, Wenfei Li, Shuqin Chen, Yingying Su, Tingting Hu, Xuhong Lu, Yafen Ye, Ningning Bai, Fan Hu, Xiaoya Li, Rongrong Xu, Jun Xu, Jiarui Zhao, Yan Lu, Xiaojing Ma, Ying Yang   +16 more
wiley   +1 more source

First evidence of Tityus confluens Borelli, 1899 (Buthidae) venom altering purine metabolism in rat blood cells. [PDF]

Purinergic Signal
da Silva Portilho R, Brito IL, Santos AN, Moreschi BP, de Lucena MN, Otsubo Jaques JA.   +5 more
europepmc   +1 more source

Figure 5 from One-Carbon Metabolism Inhibition Depletes Purines and Results in Profound and Prolonged Ewing Sarcoma Growth Suppression

Sara Zirpoli, Noah Copperman, Shrey Patel, A.R.W. Forrest, Zhanjun Hou, Larry H. Matherly, David M. Loeb, Antonio Di Cristofano   +7 more
openalex   +1 more source

NAD⁺ Reduction in Glutamatergic Neurons Induces Lipid Catabolism and Neuroinflammation in the Brain via SARM1

Advanced Science, Volume 13, Issue 6, 30 January 2026.
NAD⁺ homeostasis maintains neuronal integrity through opposing actions of NMNAT2 and SARM1. Loss of NMNAT2 in glutamatergic neurons reprograms cortical metabolism from glucose to lipid catabolism, depletes lipid stores, and triggers inflammation and neurodegeneration.
Zhen‐Xian Niou, Sen Yang, Andrea Enriquez, Nino A. Espinas, Anoosha Sri, Caliel D. Hines, Jason M. Tennessen, Chia‐Shan Wu, Jui‐Yen Huang, Hui‐Chen Lu   +9 more
wiley   +1 more source