Results 261 to 270 of about 128,261 (293)
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Enzymes of purine metabolism in cancer
Clinical Biochemistry, 1983In cancer cells, a marked imbalance in the enzymic pattern of purine metabolism is linked with transformation and/or progression. In chemically-induced, transplantable hepatomas in rat, the specific activities of the anabolic enzymes, IMP dehydrogenase, GMP synthetase, adenylosuccinate synthetase, adenylosuccinase, AMP deaminase and ...
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Purine metabolism in Schistosoma mansoni
International Journal for Parasitology, 1972Abstract Schistosoma mansoni has been found to have a spectrum of purine nucleotides which is similar, but not identical to mammalian cells. The principal component of this system is ATP, which is present at a level of about 5·5 × 10 −9 moles/mg worm pairs.
A W, Senft +3 more
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Purine metabolism in Trypanosoma cruzi
Molecular and Biochemical Parasitology, 1981Culture forms of Trypanosoma cruzi are incapable of synthesizing purines de novo from formate, glycine, or serine and require an exogenous purine for growth. Adenine, hypoxanthine, guanine, xanthine and their respective ribonucleosides are equal in their abilities to support growth.
R L, Berens +3 more
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Purine and Pyrimidine Metabolism in Leishmania
2008Purines and pyrimidines are indispensable to all life, performing many vital functions for cells: ATP serves as the universal currency of cellular energy, cAMP and cGMP are key second messenger molecules, purine and pyrimidine nucleotides are precursors for activated forms of both carbohydrates and lipids, nucleotide derivatives of vitamins are ...
Nicola S, Carter +4 more
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Purine Metabolism in Rat Macrophages
1984The association of deficiencies of purine metabolic enzymes with immunodeficiency diseases has stimulated research in purine metabolism of lymphoid cells. Up to now our knowledge about purine metabolism of other cells of the immune system, e.g., macrophages, is relatively limited.
J, Barankiewicz, A, Cohen
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Nutritional State and Purine Metabolism
1977Hyperuricemia and gout are multifarious disorders of purine metabolism with heredity as genetic base and exogenic environmental factors which are prevailing of alimentary nature including overcaloric and fatty nutrition and alcohol consumption. These latter factors may be able to induce the manifestation of clinical gout.
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Evolutionary impacts of purine metabolism genes on mammalian oxidative stress adaptation
Zoological Research, 2022Ran Tian, Han Guo, Inge Seim
exaly