Results 251 to 260 of about 1,020,918 (293)

Purine Metabolism in Feline Lymphomas

Veterinary Pathology, 1990
Deficiency of the purine metabolic enzyme adenosine deaminase causes severe immunodeficiency. Retroviruses have been reported to decrease the activity of adenosine deaminase, and many retroviruses, including feline leukemia virus, cause immunodeficiency.
E A, Copelan, K S, Waddell, S C, Johnson, L, Mathes   +3 more
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Disorders of purine biosynthesis metabolism

Molecular Genetics and Metabolism, 2022
Purines are essential molecules that are components of vital biomolecules, such as nucleic acids, coenzymes, signaling molecules, as well as energy transfer molecules. The de novo biosynthesis pathway starts from phosphoribosylpyrophosphate (PRPP) and eventually leads to the synthesis of inosine monophosphate (IMP) by means of 10 sequential steps ...
Joseph P, Dewulf, Sandrine, Marie, Marie-Cécile, Nassogne   +2 more
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Purine metabolism in human lymphocytes

Blut, 1979
In peripheral human blood lymphocytes the uptake and metabolism of adenine, guanine, and hypoxanthine was investigated. This was achieved by incubation of purified lymphocytes with 14C-purine bases, separation of cells from the incubation medium by a rapid filtration technique, and subsequent separation of the acid soluble material by thin-layer ...
M M, Müller, G, Pischek, O, Scheiner, H, Stemberger, G, Wiedermann   +4 more
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Neurological presentations of inborn errors of purine and pyrimidine metabolism

European Journal of Paediatric Neurology
Purines and pyrimidines are essential components as they are the building blocks of vital molecules, such as nucleic acids, coenzymes, signalling molecules, as well as energy transfer molecules.
Marie-Cécile Nassogne, Joseph P Dewulf, Sandrine Marie   +2 more
exaly   +2 more sources

Purine metabolism in Trypanosoma cruzi

Molecular and Biochemical Parasitology, 1981
Culture forms of Trypanosoma cruzi are incapable of synthesizing purines de novo from formate, glycine, or serine and require an exogenous purine for growth. Adenine, hypoxanthine, guanine, xanthine and their respective ribonucleosides are equal in their abilities to support growth.
R L, Berens, J J, Marr, S W, LaFon, D J, Nelson   +3 more
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Purine and pyrimidine metabolism in the trypanosomatidae

Molecular and Biochemical Parasitology, 1984
The pathways leading to purine and pyrimidine nucleotide production in members of the family Trypanosomatidae are discussed with special emphasis on data relating to pathogenic species published from 1974 to 1983 inclusive. Trypanosomes and leishmania in general lack a de novo purine biosynthetic pathway, but have a multiplicity of possible routes for ...
D J, Hammond, W E, Gutteridge
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Purine metabolism in Schistosoma mansoni

International Journal for Parasitology, 1972
Abstract Schistosoma mansoni has been found to have a spectrum of purine nucleotides which is similar, but not identical to mammalian cells. The principal component of this system is ATP, which is present at a level of about 5·5 × 10 −9 moles/mg worm pairs.
A W, Senft, R P, Miech, P R, Brown, D G, Senft   +3 more
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Purine and Pyrimidine Metabolism in Leishmania

2008
Purines and pyrimidines are indispensable to all life, performing many vital functions for cells: ATP serves as the universal currency of cellular energy, cAMP and cGMP are key second messenger molecules, purine and pyrimidine nucleotides are precursors for activated forms of both carbohydrates and lipids, nucleotide derivatives of vitamins are ...
Nicola S, Carter, Phillip, Yates, Cassandra S, Arendt, Jan M, Boitz, Buddy, Ullman   +4 more
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Enzymes of purine metabolism in cancer

Clinical Biochemistry, 1983
In cancer cells, a marked imbalance in the enzymic pattern of purine metabolism is linked with transformation and/or progression. In chemically-induced, transplantable hepatomas in rat, the specific activities of the anabolic enzymes, IMP dehydrogenase, GMP synthetase, adenylosuccinate synthetase, adenylosuccinase, AMP deaminase and ...
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Purine metabolism in primitive erythrocytes

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1973
Abstract 1. 1. The activities of AMP kinase, GMP kinase, NDP kinase, PNPase and HGPRTase were determined in the erythrocytes of seal, eel, hagfish and dogfish. 2. 2. Erythrocytic NDP kinase activities were high and electrophoretically heterogeneous in all species examined. 3. 3.
R E, Parks, P R, Brown, Y C, Cheng, K C, Agarwal, C M, Kong, R P, Agarwal, C C, Parks   +6 more
openaire   +2 more sources