Results 231 to 240 of about 128,261 (293)

Development and production of allogeneic cord blood‐derived red blood cell concentrates for transfusion to extremely preterm neonates, the All‐Cord study

Transfusion, EarlyView.
Abstract Background Extremely preterm neonates often require red blood cell (RBC) transfusions derived from adult donors. These transfusions introduce adult hemoglobin into a neonatal hematopoietic system dominated by fetal hemoglobin (HbF), shifting the oxygen‐dissociation curve and increasing oxygen delivery to immature tissues.
Jip H. van Daelen, Joyce Bestebroer, Herbert Korsten, Christie Vermeulen, Irwin K. M. Reiss, Enrico Lopriore, Pauline M. Snijder, Elise J. Huisman, Thomas R. L. Klei   +8 more
wiley   +1 more source

Uric Acid, the End-Product of Purine Metabolism, Mitigates Tau-Related Abnormalities: Comparison with DOT, a Non-Antibiotic Oxytetracycline Derivative. [PDF]

Biomolecules
Andretto de Mattos B, Tomas-Grau RH, Alves Fernandes TA, González-Lizárraga F, Tourville A, Ciss I, Brunel JM, Chehin R, Lannuzel A, Ferrié L, Raisman-Vozari R, Figadère B, Del Bel E, Michel PP.   +13 more
europepmc   +1 more source

Skeletal muscle adaptation to muscle activity and hypoxia: Differential structural and metabolic remodelling

The Journal of Physiology, EarlyView.
Abstract figure legend There has been controversy about the structural (capillary) response of skeletal muscle to altered O2 status, involving decreased supply (hypoxia) or increased demand (activity). Here we demonstrate that seven days of activation of skeletal muscle by indirect electrical stimulation led to significant expansion of the capillary ...
David Hauton, Roger W.P. Kissane, James McCullagh, Stuart Egginton   +3 more
wiley   +1 more source

Rapid Identification of Edible Insect Species in Food Using MALDI‐TOF Mass Spectrometry

Rapid Communications in Mass Spectrometry, Volume 40, Issue 13, 15 July 2026.
ABSTRACT Rationale Edible insects are emerging as sustainable, nutritious ‘foods of the future’ and are gradually introduced to the European market as novel foods. Ensuring consumer safety and preventing fraud requires legal regulation, which in turn depends on reliable analytical methods.
David Straka, Alena Meledina, Tatiana Anatolievna Smirnova, Jana Hajslova, Lenka Kourimska, Martin Kulma, Katerina Sebelova, Ondrej Pospisil, Anezka Kopecka, Stepanka Kuckova   +9 more
wiley   +1 more source

Vagus Nerve Stimulation Paired With Tones Alters the Auditory Cortex Proteome in a Rat Model of Rett Syndrome

Developmental Neurobiology, Volume 86, Issue 3, July 2026.
ABSTRACT Rett syndrome is a neurodevelopmental disorder caused by an X‐linked mutation of the MeCP2 gene. Individuals with Rett syndrome, as well as rodent models of this disorder, demonstrate abnormal cortical responses to sound, which impair auditory discrimination ability.
Isabella K. Myers, Fang Bian, Maria P. Solano, Yara El Zoghby, Diana Tavares‐Ferreira, Tanya Danaphongse, Crystal T. Engineer   +6 more
wiley   +1 more source

STUDIES ON THE EFFECTS OF PURINES ON METABOLISM

Journal of Biological Chemistry, 1946
openaire   +2 more sources

The Silent Link: Exploring the Impact of Periodontal Diseases on Head and Neck Carcinogenesis

Clinical and Experimental Dental Research, Volume 12, Issue 3, June 2026.
ABSTRACT Objectives Oral dysbiosis can accelerate the progression of head and neck squamous cell carcinoma (HNSCC) by fostering a pro‐inflammatory, immunosuppressive, and metabolically altered environment. This narrative review examines the relationships between periodontitis‐associated bacteria and HNSCC, focusing on their impact on oncogenic pathways,
Yashmin Afshar, Nima Rezaei
wiley   +1 more source

Yeast Culture Supplementation Improves Meat Quality by Enhancing Immune Response and Purine Metabolism of Small-Tail Han Sheep (<i>Ovis aries</i>). [PDF]

Int J Mol Sci
Bai X, Wang L, Sun H, Sun L, An J, Fu S, Zhao M, Liu F, Ren X, Liu Z, He J, Liu Y.   +11 more
europepmc   +1 more source

Efficient Gene Expression System in Medaka Embryos Enables Functional Characterization of nt5c1a Paralogs Involved in Inosine Monophosphate Metabolism

genesis, Volume 64, Issue 3, June 2026.
ABSTRACT Optimizing transient expression systems in fish embryos is crucial for rapid gene function analysis. Here, we established an efficient system in medaka (Oryzias latipes) embryos by evaluating nucleic acid type and injection site. Our results revealed that injecting the elongation factor 1αA (ef1αA) promoter‐driven plasmid into the yolk yielded
Yu Murakami, Tomohisa Horibe, Masashi Ando, Toru Kobayashi   +3 more
wiley   +1 more source

Heme Metabolism‐Derived Carbon Monoxide Regulates Skeletal Muscle Function

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Background Heme oxygenases, HO‐1 (Hmox1) and HO‐2 (Hmox2), regulate skeletal muscle homeostasis by degrading heme and generating carbon monoxide (CO), a bioactive signalling molecule. Although HO‐1 is known to influence muscle fibre composition and mitochondrial function, the role of HO‐2 in activity‐dependent neuromuscular plasticity remains ...
Rodrigo W. Alves de Souza, Hyo In Kim, Paula Ketilly Nascimento Alves, Ailma Oliveira da Paixão, Ashlee Rasmussen, Sidharth Shankar, James Harbison, Vanessa Azevedo Voltarelli, Leo E. Otterbein   +8 more
wiley   +1 more source