Results 231 to 240 of about 1,551,682 (283)

Yeast Culture Supplementation Improves Meat Quality by Enhancing Immune Response and Purine Metabolism of Small-Tail Han Sheep (<i>Ovis aries</i>). [PDF]

Int J Mol Sci
Bai X, Wang L, Sun H, Sun L, An J, Fu S, Zhao M, Liu F, Ren X, Liu Z, He J, Liu Y.   +11 more
europepmc   +1 more source

First evidence of Tityus confluens Borelli, 1899 (Buthidae) venom altering purine metabolism in rat blood cells. [PDF]

Purinergic Signal
da Silva Portilho R, Brito IL, Santos AN, Moreschi BP, de Lucena MN, Otsubo Jaques JA.   +5 more
europepmc   +1 more source

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Targeting purine metabolism-related enzymes for therapeutic intervention: A review from molecular mechanism to therapeutic breakthrough

International Journal of Biological Macromolecules
Purines are ancient metabolites with established and emerging metabolic and non-metabolic signaling attributes. The expression of purine metabolism-related genes is frequently activated in human malignancies, correlating with increased cancer ...
Chenyang Yuan, Kaifeng Guan, Hong Zeng   +2 more
exaly   +2 more sources

The purine metabolism of human erythrocytes

Biochemistry (Moscow), 2006
This review summarizes currently available information about a crucial part of erythrocyte metabolism, that is, purine nucleotide conversions and their relationships with other conversion pathways. We describe the cellular resynthesis, interconversion, and degradation of purine compounds, and also the regulatory mechanisms in the conversion pathways ...
Wioleta Dudzińska, M Suska
exaly   +3 more sources

A Photoactivated Sorafenib-Ruthenium(II) Prodrug for Resistant Hepatocellular Carcinoma Therapy through Ferroptosis and Purine Metabolism Disruption.

Journal of Medicinal Chemistry, 2022
The curative effect of sorafenib in hepatocellular carcinoma (HCC) is limited and sorafenib resistance remains a major obstacle for HCC. To overcome this obstacle, a new photoactive sorafenib-Ru(II) complex Ru-Sora has been designed. Upon irradiation (λ =
Yidan Lai, Nong Lu, Shuangling Luo, Haobing Wang, Pingyu Zhang   +4 more
semanticscholar   +1 more source

The Role of Probiotics in Purine Metabolism, Hyperuricemia and Gout: Mechanisms and Interventions

Food reviews international (Print), 2021
Hyperuricemia and gout are metabolic diseases characterized with high serum urate and impact human health significantly. Although some drugs have been developed to treat gout, hyperuricemia represents a substantial health problem.
Armachius James, H. Ke, Ting Yao, Yousheng Wang   +3 more
semanticscholar   +1 more source

FRUCTOSE AND PURINE METABOLISM

Acta Medica Scandinavica, 1972
Abstract.The interactions between fructose and purine metabolism are reviewed. Hyperuricemia and increased production of uric acid after fructose administration have been documented in man as well as in the rat. These effects appear to be dependent on the rapid phosphorylation of fructose, mainly in the liver.
K O, Raivio, M, Kekomäki, P, Mäenpää
openaire   +2 more sources

New insights into purine metabolism in metabolic diseases: role of xanthine oxidoreductase activity.

American Journal of Physiology. Endocrinology and Metabolism, 2020
Xanthine oxidoreductase (XOR) consists of two different forms, xanthine dehydrogenase (XDH) and xanthine oxidase (XO), and is a rate-limiting enzyme of uric acid production from hypoxanthine and xanthine. Uric acid is the end-product of purine metabolism
M. Furuhashi
semanticscholar   +1 more source

Bovine milk exosomes attenuate the alteration of purine metabolism and energy status in IEC-6 cells induced by hydrogen peroxide.

Food Chemistry, 2021
Evidence suggests that dietary depletion of bovine milk exosomes and their cargos causes a loss of circulating microRNAs and a series of health problems.
Lanfang Wang, Xinyan Wang, Zhexi Shi, Li Shen, Jing Zhang, Jun Zhang   +5 more
semanticscholar   +1 more source