Environmental Microbiology Reports, Volume 18, Issue 4, August 2026.Histidine accumulation promotes tetracycline‐induced persister formation in V. splendidus. It enhances membrane potential and upregulating the efflux pump gene, thereby reducing antibiotic susceptibility. ABSTRACT Vibrio splendidus is an opportunistic pathogen widely distributed in marine environments, animal tissues and seabed sediments. It can infect
Yanan Li +4 more
wiley +1 more source
<i>Isodon lophanthoides</i> alleviates liver fibrosis via modulation of purine metabolism and NF-κB signaling pathway: insights from multi-omics analysis. [PDF]
Front PharmacolChen K +7 more
europepmc +1 more source
Enriched Metabolic Phenotyping Refines Phenotypic Resolution of Type 2 Diabetes
Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 6674-6686, August 2026.ABSTRACT Aims Data‐driven clustering studies of type 2 diabetes (T2D) based on limited routine clinical variables have reproducibly described major metabolic subgroups, including severe insulin‐deficient diabetes (SIDD), severe insulin‐resistant diabetes (SIRD), mild obesity‐related diabetes and mild age‐related diabetes.
Min Wang +6 more
wiley +1 more source
STUDIES ON THE EFFECTS OF PURINES ON METABOLISM
Journal of Biological Chemistry, 1946 openaire +2 more sources
Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 6561-6575, August 2026.ABSTRACT Aims Similar to blood, saliva contains a broad range of biomarkers and may offer a non‐invasive, repeatable specimen for endocrine and metabolic assessment. This review aims to synthesise and evaluate recent advances in the clinical translation of salivary biomarkers, while providing a critical assessment of the diagnostic reliability and ...
Chuyan Yu +7 more
wiley +1 more source
Climate change and crop resilience: harnessing metabolomics for predicting stress tolerance
New Phytologist, Volume 251, Issue 3, Page 975-995, August 2026.Summarised methodology for metabolite biomarker discovery and genomic targets selection for those metabolites to predict high‐throughput phenotypic and agronomic traits of interest for direct uptake in breeding programmes. Summary Global warming is driving climate change to levels not experienced since the advent of agriculture, primarily due to ...
Agyeya Pratap +3 more
wiley +1 more source
Uric Acid, the End-Product of Purine Metabolism, Mitigates Tau-Related Abnormalities: Comparison with DOT, a Non-Antibiotic Oxytetracycline Derivative. [PDF]
BiomoleculesAndretto de Mattos B +13 more
europepmc +1 more source
A Non‐Host Pathogen Elicitor Induces Blast Resistance Mediated by OsNAC78‐Pir7b Module in Rice
Plant, Cell &Environment, Volume 49, Issue 8, Page 4894-4906, August 2026.ABSTRACT Plants exhibit broad‐spectrum and persistent resistance induced by non‐host pathogens. Previous studies have found that syringolin A secreted by Pseudomonas syringae pv. syringae can activate the expression of defense‐related gene Pir7b in non‐host rice, but the underlying mechanism remains ambiguous.
Yunjie Xie +11 more
wiley +1 more source
Patchoulene epoxide mitigates colitis and hepatic damage induced by dextran sulfate sodium by regulating the colonic microbiota and purine metabolism. [PDF]
Front ImmunolChen L +11 more
europepmc +1 more source
Utilizing integrated bioinformatics and machine learning approaches to elucidate biomarkers linking sepsis to purine metabolism-associated genes. [PDF]
Sci RepLiang F, Zheng M, Lu J, Liu P, Chen X.
europepmc +1 more source