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[Purine nucleoside phosphorylase (PNP)].
Nihon rinsho. Japanese journal of clinical medicine, 1997PNP, encoded by 6 exons on human chromosome 14q13, is a homotrimetic enzyme of approximately 96 k dalton. This enzyme reversibly catalyzes the phosphorolysis of purine nucleoside to their respective purine bases and the corresponding pentose-1-phosphate.
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Purine nucleoside phosphorylase deficiency.
Immunodeficiency reviews, 1991Purine nucleoside phosphorylase (PNP) deficiency is a rare inherited disease accounting for approximately 4% of patients with severe combined immunodeficiency. Thirty-three patients have been reported. PNP-deficient patients suffer from recurrent infections, usually beginning in the first year of life. Two thirds of patients have evidence of neurologic
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Thyroid purine nucleoside phosphorylase
Biochimica et Biophysica Acta (BBA) - Enzymology, 1979Jeffrey D. Carlson, Allan G. Fischer
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Crystal Structure of Purine Nucleoside Phosphorylase from Thermus thermophilus
Journal of Molecular Biology, 2004Tomoe Kitao +2 more
exaly
Inhibitors of purine nucleoside phosphorylase
Biochemical Pharmacology, 1982Johanna D. Stoeckler +4 more
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