This study identifies ferroptosis as a key driver of diabetes and its complications via iron metabolism and lipid peroxidation, elucidates organelle interactions underlying cell vulnerability, and provides insights for targeted therapies against metabolic disorders.
Zheng Wang +10 more
wiley +1 more source
Newer agents in antiplatelet therapy: a review
Jennifer Yeung, Michael HolinstatCardeza Foundation for Hematologic Research, Department of Medicine, Thomas Jefferson University, Philadelphia, PA, USAAbstract: Antiplatelet therapy remains the mainstay in preventing aberrant platelet activation in ...
Yeung J, Holinstat M
doaj
Crystal structure of purinergic receptor P2Y G protein–coupled 12 (P2RY12; P2Y12) bound to an antagonist [PDF]
openaire +1 more source
ATP-related purinergic signaling via P2Y12 contributes to airway epithelial barrier integrity. [PDF]
Tsuya K +9 more
europepmc +1 more source
Inhibition of (interstitial) P2Y<sub>6</sub> receptors attenuates fibrosis progression. [PDF]
Süß LM +7 more
europepmc +1 more source
Methodological guidelines for P2X receptor assays and data interpretation. [PDF]
Gorecki DC +28 more
europepmc +1 more source
Purinergic signaling in osteoarthritis: Mechanistic insights into pathogenesis and therapeutic targeting. [PDF]
Li H +5 more
europepmc +1 more source
P2 Receptors as Therapeutic Targets in Allergic Rhinitis: Insights From the Use of Natural Products and Preclinical Studies. [PDF]
Pereira TC, Rocha L, Faria RX.
europepmc +1 more source
Proteasomal-dependent endothelial P2Y<sub>6</sub> receptor downregulation as an adaptive mechanism limiting monocyte adhesion during intestinal schistosomiasis. [PDF]
Oliveira NF +5 more
europepmc +1 more source

