Results 111 to 120 of about 99,634 (353)

Efficient Synthesis of Novel Triazolo[5,1-b]purines by Diacetoxyiodobenzene-Mediated Oxidative Cyclization of Schiff Bases

open access: yesReactions
In this work, we have developed a method for synthesizing new 8-substituted triazolo[5,1-b]purines using diacetoxyiodobenzene as an oxidizing agent with good yields (59–67%).
Artyom O. Neymash   +5 more
doaj   +1 more source

DNA viewed as an out-of-equilibrium structure

open access: yes, 2013
The complexity of the primary structure of human DNA is explored using methods from nonequilibrium statistical mechanics, dynamical systems theory and information theory.
Nicolis, C., Nicolis, G., Provata, A.
core   +1 more source

Synthesis of Adenine Nucleosides with a Reactive (β-Iodovinyl)sulfone or (β-Keto)sulfone Group at the C2 Position and Their Polymerase-Catalyzed Incorporation into DNA

open access: yesMolecules
Iodosulfonylation of an ethynyl group at the C2 position of 2′-deoxyadenosine or adenosine with TsI provides (E)-2-(β-iodovinyl)sulfones. The latter undergo nucleophilic substitution with amines via an addition–elimination to give β-sulfonylvinylamines ...
A. Hasan Howlader   +4 more
doaj   +1 more source

Purine Phosphoribosyltransferases [PDF]

open access: yesJournal of Biological Chemistry, 2000
S P, Craig, A E, Eakin
openaire   +2 more sources

A systematically coarse-grained model for DNA, and its predictions for persistence length, stacking, twist, and chirality

open access: yes, 2009
We introduce a coarse-grained model of DNA with bases modeled as rigid-body ellipsoids to capture their anisotropic stereochemistry. Interaction potentials are all physicochemical and generated from all-atom simulation/parameterization with minimal ...
Alex Morriss-Andrews   +8 more
core   +1 more source

Ribozymes for RNA‐Catalyzed RNA Methylation and Labeling

open access: yesAngewandte Chemie International Edition, Volume 65, Issue 23, 1 June 2026.
Ribozymes are powerful tools for site‐specific RNA modification. Their activities range from installing tags and fluorophores to generating natural RNA methylations, making them valuable tools to uncover the many functions that RNA plays in nature.
Carolin P. M. Scheitl   +1 more
wiley   +1 more source

Polyoxotungstates in Molecular Boxes of Purine Bases

open access: yesCrystals, 2014
Three new compounds, (GuaH)4[W10O32](H2O)4 (1), (ThbH)3(H3O)[(W10O32](H2O)7.5 (2) and (ThbH)2[W6O19](H2O)2 (3) (GuaH = guaninium, thbH = theobrominium) were synthesized in acidified acetonitrile solutions.
Vladislav Kulikov, Gerd Meyer
doaj   +1 more source

P2X4 signalling contributes to hyperactivity but not pain sensitization comorbidity in a mouse model of attention deficit/hyperactivity disorder

open access: yesFrontiers in Pharmacology
Introduction: Attention deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder characterized by hyperactivity, inattention, and impulsivity that often persist until adulthood.
Sarah Bou Sader Nehme   +11 more
doaj   +1 more source

Solvable models of neighbor-dependent nucleotide substitution processes

open access: yes, 2005
We prove that a wide class of models of Markov neighbor-dependent substitution processes on the integer line is solvable. This class contains some models of nucleotide substitutions recently introduced and studied empirically by molecular biologists.
Bérard, Jean   +2 more
core   +4 more sources

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