Results 161 to 170 of about 40,111 (263)

Analysis of purine in purine-rich cauliflower

Analysis of purine in purine-rich cauliflower
Purine is a general term for purine nucleotides, nucleosides, bases, and nucleic acid. The amount of purine nucleotides, nucleosides, and bases in purine-rich cauliflower was determined with the use of LC-MS and HPLC, and the ratio of these molecules were compared with in raw and in heated condition.
openaire  

Cooperativity in E. coli aspartate transcarbamoylase is tuned by allosteric breathing. [PDF]

Nat Commun
Miller RC, Patterson MG, Bhatt N, Pei X, Ando N.   +4 more
europepmc   +1 more source

Metabolome Diversity Enhances Resistance of Intertidal Clams to Thermal Stress

Integrative Zoology, EarlyView.
Meretrix species are widely distributed intertidal bivalves in China with significant ecological and economic importance, which are sensitive to thermal stress. Our results showed that thermal environments of clam habitats shaped metabolome diversity, which can enhance the resistance of intertidal clams to thermal stress.
Zhi Hu, Xiang‐Tao Wei, Xiaonie Lin, Linxuan Ma, Tianzhe Zhang, Yunwei Dong   +5 more
wiley   +1 more source

PMO's protective wrap: Unraveling its surfactant-mediated stabilization for next-generation antisense therapies. [PDF]

Mol Ther Nucleic Acids
Sharma SN, Gupta A, Sinha S.
europepmc   +1 more source

Distinct Immunometabolic Profiles in Finnish and Russian Karelian Adolescents With Contrasting Allergy Risk

Allergy, EarlyView.
We compared Finnish and Russian Karelian adolescents with contrasting allergy burden using integrated proteomic, metabolomic, and transcriptomic profiling. Finnish adolescents showed a broader pro‐inflammatory PBMC secretory profile consistent with a low‐grade inflammatory phenotype.
Nanna Fyhrquist, Matilda Riskumäki, Piia Karisola, Anni Nieminen, Tiina Laatikainen, Hanna Sinkko, Laura Paalanen, Pekka Jousilahti, Erkki Vartiainen, Mika J. Mäkelä, Tari Haahtela, Harri Alenius   +11 more
wiley   +1 more source

Disruption of purine <i>de novo</i> synthesis pathway impairs membrane homeostasis, intracellular survival, and virulence of <i>Brucella melitensis</i>. [PDF]

Front Microbiol
Yang G, Li M, Li Y, Chen S, Qu J, Li J, Wang S, Bao Y, Qi J, Dou Y, Tian M.   +10 more
europepmc   +1 more source

Adenosine—A Regulator of Human Testicular Peritubular Cells

Andrology, EarlyView.
ABSTRACT Background Extracellular purines, in particular ATP and adenosine, are regulators of physiological and pathophysiological processes throughout the human body. Roles in the human testis are emerging and include actions on peritubular cells, which form the wall of seminiferous tubules.
Lina Scholz, Annika Liebich, Youli Stepanov, Jan B. Stöckl, Mirko Peitzsch, Michaela Schneider, Julia Schneider, Nicole Kreitmair, Matthias Trottmann, Frank‐Michael Köhn, Jovica Ninkovic, Thomas Fröhlich, Artur Mayerhofer   +12 more
wiley   +1 more source

Nucleotide salvage, genome instability, and potential therapeutic applications. [PDF]

Nucleic Acids Res
Wang P, Wang C, Wang Y.
europepmc   +1 more source

Review Article: The Impact of the Gut Microbiome on Ulcerative Colitis Pharmacotherapy

Alimentary Pharmacology &Therapeutics, EarlyView.
The gut microbiome modulates ulcerative colitis pharmacotherapy through microbial drug metabolism, immune regulation and altered drug bioavailability. Microbial composition influences response to aminosalicylates, corticosteroids, immunomodulators, biologics and small molecules, while microbiome‐targeted therapies show emerging promise.
Kate Collins, Srinivas Kamath, Rachel H. Davis, Samuel P. Costello, Robert V. Bryant, Alice S. Day, Paul Joyce   +6 more
wiley   +1 more source

Distribution of extraterrestrial nucleobases, other N-heterocycles, and their precursors in a sample from asteroid Bennu. [PDF]

Commun Chem
Oba Y, Koga T, Takano Y, Naraoka H, Hirakawa Y, Sunami S, Furukawa Y, Yamazaki T, Tomaru T, Dworkin JP, Glavin DP, Connolly HC, Lauretta DS.   +12 more
europepmc   +1 more source