Results 191 to 200 of about 12,040,588 (301)

Cerebellar Zonal Patterning Relies on Purkinje Cell Neurotransmission

Journal of Neuroscience, 2014
Joshua J. White, M. Arancillo, Trace L. Stay, Nicholas A George-Jones, Sabrina L. Levy, D. Heck, R. Sillitoe   +6 more
semanticscholar   +1 more source

Phototriggered Morphological and Compositional Change of UGGAA Repeat RNA Foci by Photoswitchable RNA‐Binding Ligand

Angewandte Chemie, Volume 138, Issue 18, 27 April 2026.
We here developed a molecular tool for the optical control of UGGAA repeat RNA foci, a pathological hallmark of spinocerebellar ataxia type 31 (SCA31). The photoswitchable RNA‐binding ligand enabled reversible control of the RNA foci. UV irradiation induced the growth of the RNA foci, while subsequent visible light irradiation dissolved the structure ...
Yusuke Fujiwara, Tomonori Shibata, Chikara Dohno   +2 more
wiley   +2 more sources

Temporal dynamics of Purkinje cell-intrinsic excitability governs cerebellar systems consolidation. [PDF]

iScience
Seo J, Kim YG, Lee YS, Kim SJ.
europepmc   +1 more source

The ER/Golgi Protein FNDC3B Facilitates Climbing Fibre to Purkinje Cell Synapse Elimination in the Developing Mouse Cerebellum. [PDF]

Eur J Neurosci
Mercier CL, Watanabe T, Okuno Y, Matsuyama K, Kushibe K, Denny H, Miyazaki T, Yamasaki M, Kawamura M, Abe M, Sakimura K, Watanabe M, Uesaka N, Kano M.   +13 more
europepmc   +1 more source

Using cerebellar Purkinje cell models at different levels of abstraction as a read-out mechanism for pattern recognition in a biologically detailed granular layer model [PDF]

, 2019
Davey, Neil, Kadir, Shabnam, Katakura, Ohki, Maex, Reinoud, Steuber, Volker   +4 more
core   +2 more sources

PCP4 regulates Purkinje cell excitability and cardiac rhythmicity.

Journal of Clinical Investigation, 2014
Eugene E Kim, Akshay Shekhar, Jia Lu, Xianming Lin, Fangyu Liu, Jie Zhang, M. Delmar, G. Fishman   +7 more
semanticscholar   +1 more source

Pacemaking in the heart: a redundant and robust system of mutually entrained oscillators driving cardiac automaticity

The Journal of Physiology, Volume 604, Issue 9, Page 3504-3512, 1 May 2026.
Abstract figure legend Cardiac pacemaking: the redundant and robust organ‐to‐subcellular system driving the spontaneous electrical activity responsible for regular, rhythmic excitation of the heart. Abstract The heart is an electrically controlled, mechanical pump that provides a constant supply of blood to the body.
Eilidh A. MacDonald, T. Alexander Quinn
wiley   +1 more source

Cerebellar Purkinje cell stripe patterns reveal a differential vulnerability and resistance to cell loss during normal aging in mice. [PDF]

Elife
Donofrio SG, Brandenburg C, Brown AM, Lin T, Lu HC, Sillitoe RV.   +5 more
europepmc   +1 more source

Structure mirroring function: What's the ‘matter’ with the funny current?

The Journal of Physiology, Volume 604, Issue 9, Page 3513-3532, 1 May 2026.
Abstract figure legend The ‘funny’ (If) current of cardiac pacemaker cells has been first identified in the late 1970s as a major mechanism in the generation and control of cardiac pacemaking. Decades of studies have since described the properties of the funny current and of its molecular components, HCN channels, in the heart and brain, providing the ...
Andrea Saponaro, Dario DiFrancesco
wiley   +1 more source

Purkinje Cell Spatial Correlation Dynamics Are Key to Cerebellar Cortical Contributions to Behavior. [PDF]

J Neurosci
Streng ML, Carter RE, Kottke BW, Togneri K, Wasserman E, Rajendran V, Kodandaramaiah SB, Krook-Magnuson E, Ebner TJ.   +8 more
europepmc   +1 more source